Determination of residual by headspace gas chromatography organic solvents in piroxicam

LI Yu; ZHAO Jing-xia; YANG Gen-jin; DONG Xin; LI Ling; SU Li; ZHANG Wei

Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review, editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code

x Close Forever Close

PDF
Cite
Share

facebook

twitter

google

linkedin

Volume 29 Issue 1

Turn off MathJax

Article Contents

Article Navigation > Journal of Pharmaceutical Practice and Service > 2011 > 29(1): 31-32

LI Yu, ZHAO Jing-xia, YANG Gen-jin, DONG Xin, LI Ling, SU Li, ZHANG Wei. Determination of residual by headspace gas chromatography organic solvents in piroxicam[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(1): 31-32.

Citation:

LI Yu, ZHAO Jing-xia, YANG Gen-jin, DONG Xin, LI Ling, SU Li, ZHANG Wei. Determination of residual by headspace gas chromatography organic solvents in piroxicam[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(1): 31-32.

Determination of residual by headspace gas chromatography organic solvents in piroxicam

Center of Pharmaceutical Analysis, College of Pharmacy, Second Military Medical University, Shanghai 200433,China

Received Date: 2009-09-18
Rev Recd Date: 2009-11-26

Abstract

Objective To establish a headspace capillary gas chromatgraphy for determination the residual organic solvents in piroxicam. Methods The residual solvents in piroxicam which are methanol , ethanol, toluene and dimethybenzene were determined by headspace GC on HP-INNOWax column(30 m×0.32 mm×0.25 μm),with FID detector,high purity nitrogen as the carry gas. Results Four residual organic solvents consisting of methanol, ethanol, toluene and dimethybenzene in piroxicam were completely separated and the samples coincided with the requirements. Conclusion The method is sensitive and accurate. It is suitable to the determination of residual organic solvents in piroxicam.
- headspace gas chromatgraphy,
- piroxicam,
- residual organic solvents

References

[1]	《中国药典》2005年版.二部[S]. 2005: 247.
[2]	曹玲,唐树荣,万嵘. HPLC法测定吡罗昔康注射液的含量[J]. 药物分析杂志,2001, 21(1): 47.
[3]	郭萌,高爱军. 吡罗昔康片中吡罗昔康的含量测定及含量均匀度检查[J].中华实用中西医杂志, 2007, 20(10): 919.
[4]	李英华,吕秀阳,吕丽丽,等. 顶空气相色谱法在药物分析中的应用[J]. 药物分析杂志, 2005, 25(11): 1404.

Proportional views

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Get Citation

PDF

XML

Article Metrics

Article views(2630) PDF downloads(106) Cited by()

Proportional views