Establishment of bacterial endotoxins test in extracts injection from rabbit skin inflamed by vaccinia virus
- Received Date: 2010-08-12
- Rev Recd Date: 2010-11-21
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Key words:
- bacterial endotoxins /
- tachypleus amebocyte lysate /
- extracts injection from rabbit skin inflamed by vaccinia virus /
- the interference test
Abstract: Objective To establish a method for the detection of bacterial endotoxin in extracts injection from rabbit skin inflamed by vaccinia virus. Methods The interference test was carried out according to the guideline and procedure specified in appendix Ⅺ E, volume two, chinese pharmacopoeia 2010 edition. Results By using tachypleus amebocyte lysates which sensitivity was 0.5 EU/ml, the sample did not interfere with the bacterial endotoxins test when it was diluted 100 times. Conclusion The established method of bacterial endotoxins test for extracts injection from rabbit skin inflamed by vaccinia virus was feasible.
Citation: | WANG Zong-chun, ZHOU Yan-an, ZHANG Hong. Establishment of bacterial endotoxins test in extracts injection from rabbit skin inflamed by vaccinia virus[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(2): 128-130. |