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CHEN Shu-min, TIAN Wen-yuan, JIANG Hong. Application of antibacterial drugs of 161 patients in perioperative period[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(2): 139-141,145.
Citation: CHEN Shu-min, TIAN Wen-yuan, JIANG Hong. Application of antibacterial drugs of 161 patients in perioperative period[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(2): 139-141,145.

Application of antibacterial drugs of 161 patients in perioperative period

  • Received Date: 2010-06-23
  • Rev Recd Date: 2010-08-04
  • Objective To investigate the utilization of perioperative antibacterial agents in Fuxing Hospital,and provide references for rational use of drugs in clinic. Methods 161 cases of patients were sampled randomly from the operation cases from June to December,2009. The application of perioperative antibacterial agents was investigated according to Clinical Guidelines for Antibacterial Agents. Results The precautionary use of perioperative antibacterial drugs was 100% among the patients in our hospital, which involves 10 sorts and 19 varieties. The top five are ornidazole, cefuroxime, cefminox, azlocilin, metronidazole. The combined utilization rate of antibacterial agents was 57.76%. The combined utilization rate of typeⅠ was 47.92%. 57.14 percent of the patients started to use antibacterial drugs on 0.5 to 2 h before operation, and the average course of antibacterial drugs utilization was 4.76 d, the longest course was 15 d. Conclusion The rate of perioperative antibacterial drugs utilization and combined utilization were higher. The medication indications were not clear and the application coures was too long which need further standardization management.
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    [5] 卫生部办公厅关于抗菌药物临床应用管理有关问题的通知[S]. 卫医发,〔2009〕38号.
    [6] 孙慧英,李武平.围手术期抗菌药物应用现状及管理对策[J].护理研究,2006,23(2):69.
    [7] 〔澳〕治疗指南有限公司.治疗指南:抗生素分册[M].第12版.李大魁,盛瑞媛,译.北京:化学工业出版社,2006:133.
    [8] Bratzler DW,Hock PM,Richards CUse of antimicrobial prophylax is form ajor surgery.Baseline results from the N antionl Surgial Infection Prevention project[J]. Arch Surg,2005,140:174.
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Application of antibacterial drugs of 161 patients in perioperative period

Abstract: Objective To investigate the utilization of perioperative antibacterial agents in Fuxing Hospital,and provide references for rational use of drugs in clinic. Methods 161 cases of patients were sampled randomly from the operation cases from June to December,2009. The application of perioperative antibacterial agents was investigated according to Clinical Guidelines for Antibacterial Agents. Results The precautionary use of perioperative antibacterial drugs was 100% among the patients in our hospital, which involves 10 sorts and 19 varieties. The top five are ornidazole, cefuroxime, cefminox, azlocilin, metronidazole. The combined utilization rate of antibacterial agents was 57.76%. The combined utilization rate of typeⅠ was 47.92%. 57.14 percent of the patients started to use antibacterial drugs on 0.5 to 2 h before operation, and the average course of antibacterial drugs utilization was 4.76 d, the longest course was 15 d. Conclusion The rate of perioperative antibacterial drugs utilization and combined utilization were higher. The medication indications were not clear and the application coures was too long which need further standardization management.

CHEN Shu-min, TIAN Wen-yuan, JIANG Hong. Application of antibacterial drugs of 161 patients in perioperative period[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(2): 139-141,145.
Citation: CHEN Shu-min, TIAN Wen-yuan, JIANG Hong. Application of antibacterial drugs of 161 patients in perioperative period[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(2): 139-141,145.
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