Determination of Chlorogenic acid in Qingrexiaozhong oral liquid by HPLC

SUN Xue-xiong; LUO Chen-qu

Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review, editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code

x Close Forever Close

PDF
Cite
Share

facebook

twitter

google

linkedin

Volume 29 Issue 4

Turn off MathJax

Article Contents

Article Navigation > Journal of Pharmaceutical Practice and Service > 2011 > 29(4): 278-280

SUN Xue-xiong, LUO Chen-qu. Determination of Chlorogenic acid in Qingrexiaozhong oral liquid by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(4): 278-280.

Citation:

SUN Xue-xiong, LUO Chen-qu. Determination of Chlorogenic acid in Qingrexiaozhong oral liquid by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(4): 278-280.

Determination of Chlorogenic acid in Qingrexiaozhong oral liquid by HPLC

SUN Xue-xiong¹,
LUO Chen-qu²

1.
Department of Pharmacy, Loudi Center Hospital,Loudi 417000,China
2.
Loudi Institute for Drug control, Loudi 417000 China

Received Date: 2010-07-09
Rev Recd Date: 2011-03-04

Abstract

Objective To develop a HPLC method for determining the content of Chlorogenic acid in QingRexiaozhong Oral Liquid. Methods The phenomenex Luna-C₁₈(200 mm×4.60 mm ,5 μm)was used ;the mobile phase consisted of water-1%Acetic acid (20：80),the flow rate of 1.00 ml/min,and the detecting wavelength was 326 nm.The column temperature was at 30 ℃. Results There was a good linearity for Chlorogenic Acid in the range of 0.163 1~1.087 2 μg, r=1.000(n=5),and the average recovery rate was 100.40%, RSD=1.20%(n=9). Conclusions The method was simple,accurate,reliable and reproducible,which could be available for the quality control of QingRexiaozhong Oral Liquid
- Qingrexiaozhong oral liquid,
- Chlorogenic acid,
- HPLC,
- Content determination

References

[1]	中国药典2005版.一部[S].2005:405.
[2]	王宏军,吴国娟,李焕荣,等.金银花中绿原酸提取方法的筛选及其抑菌作用[J].北京农学院学报,2003,18(4):262.
[3]	胡美芳,宋秋华,王波.高效液相色谱法测定清肺止咳颗粒中绿原酸的含量[J].中国药业 2009,18(20):34.
[4]	邱华荣,田吉,冯文学,等.青银注射液中绿原酸与樟脑的含量测定[J].中成药,2004,26(8):621.

Proportional views

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

Get Citation

PDF

XML

Article Metrics

Article views(2623) PDF downloads(427) Cited by()

Proportional views