褶合曲线分析法同时测定小儿复方苯巴比妥片中四组分的含量
Application of convolution curve method for simultaneous determination of four components in the compound children's phenobarbital tablet
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摘要: 目的 不经分离同时测定小儿复方苯巴比妥片中四组分的含量。方法 以褶合光谱为基础,结合当前最优秀的数值计算法——偏最小二乘法(PLS法)利用计算机信息处理技术的褶合曲线分析法。结果 小儿复方苯巴比妥片中阿司匹林、非那西丁、咖啡因和苯巴比妥四组分的平均回收率及相对标准偏差(RSD)分别为99.75,0.92%;100.47,0.56%;99.82,1.12%;100.08,0.86%。结论 该方法可以用于小儿复方苯巴比妥片剂的质量监控。Abstract: OBJECTIVE Without any separation, simultaneous determination of four main components in the compound children's phenobarbital tablet. METHODS Based on convolution spectrometry with the excellent cacu-lation method-PLS method used convolution spectrometry of computer information process technology. RESULTS Components of compound children's phenobarbital tablet are aspirin, phenacetin, caffine and phenobarbital. Their average recoveries and RSD were 99.75,0.92%;100.47,0.56%;99.82,1.12%;100.08,0.86%. CONCLUSION The method is used for qualitative control of compound children's phenobarbital tablet.
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Key words:
- convolution curve analytical system /
- children's phenobarbital tablet /
- aspirin /
- phenacetin /
- caffine /
- phenobarbital
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