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八角属植物中的C6-C3类化合物及其药理活性研究进展

邓华平 孙蕾 席忠新 李霞 陈程 孙连娜

邓华平, 孙蕾, 席忠新, 李霞, 陈程, 孙连娜. 八角属植物中的C6-C3类化合物及其药理活性研究进展[J]. 药学实践与服务, 2012, 30(1): 8-13. doi: 10.3969/j.issn.1006-0111.2012.01.003
引用本文: 邓华平, 孙蕾, 席忠新, 李霞, 陈程, 孙连娜. 八角属植物中的C6-C3类化合物及其药理活性研究进展[J]. 药学实践与服务, 2012, 30(1): 8-13. doi: 10.3969/j.issn.1006-0111.2012.01.003
DENG Hua-ping, SUN Lei, XI Zhong-xin, LI Xia, CHEN Cheng, SUN Lian-na. Progress on Chemical and pharmacological research of C6-C3 compounds in genus Illicium[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(1): 8-13. doi: 10.3969/j.issn.1006-0111.2012.01.003
Citation: DENG Hua-ping, SUN Lei, XI Zhong-xin, LI Xia, CHEN Cheng, SUN Lian-na. Progress on Chemical and pharmacological research of C6-C3 compounds in genus Illicium[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(1): 8-13. doi: 10.3969/j.issn.1006-0111.2012.01.003

八角属植物中的C6-C3类化合物及其药理活性研究进展

doi: 10.3969/j.issn.1006-0111.2012.01.003
基金项目: 国家重大新药创制专项(2009ZX09502-021 与药效相关的中药质量评价关键技术成果研究).

Progress on Chemical and pharmacological research of C6-C3 compounds in genus Illicium

  • 摘要: 八角属植物中富含C6-C3类化合物,结构类型多样,有苯丙素类、木质素类和独特新颖的植物醌类,并具有较好的抗炎、神经营养、抗癌和抗氧化等活性,药用开发前景广阔。本文根据国内外文献报道,对该属植物C6-C3类化合物及其药理活性研究进展进行综述,为进一步研究开发该属植物提供参考。
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    [20] Schmidt TJ, Heilmann J. Tetrahydrofuran lignans from Illicium floridanum and their activity in a luminol enhanced chemiluminescence assay[J]. Planta Med, 2000, 66(8):749.
    [21] Tang WZ, Liu YB, Yu SS, et al. New sesquiterpene lactone and neolignan glycosides with antioxidant and anti-inflammatory activities from the fruits of Illicium oligandrum[J]. Planta Med, 2007, 73(5):484.
    [22] Moriyama M, Huang JM, Yang CS, et al. Structure and neurotrophic activity of novel sesqui-neolignans from the pericarps of Illicium fargesii[J]. Tetrahedron, 2007, 63(20):4243.
    [23] Fang L, Du D, Ding GZ, et al. Neolignans and glycosides from the stem bark of Illicium difengpi[J]. J Nat Prod, 2010, 73(5):818.
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    [25] Yakushijin K, Tohshima T, Kitagawa E, et al. Studies on the constituents of the plants of Illicium Species. III. Structure elucidations of novel phytoquinoids,Illicinones and Illifunones from Illicium tashiroi MAXIM. and I. arborescens HAYATA[J]. Chem Pharm Bull, 1984, 32(1):11.
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    [28] Fukuyama Y, Okamoto K, Kubo Y, et al. New chlorine-containing prenylated C6-C3 compounds increasing choline acetyltransferase (ChAT) activity in culture of postnatal rat septal neurons from Illicium tashiroi[J]. Chem Pharm Bull, 1994, 42(10):2199.
    [29] Fukuyama Y, Shida N, Kodama M, et al. Tricycloillicinone, a novel prenylated C6-C3 compound increasing choline acetyltransferase (ChAT) activity, isolated from Illicium tashiroi[J]. Chem Pharm Bull, 1995, 43(12):2270.
    [30] Fukuyama Y, Hata Y, Kodama M. Bicycloillicinone asarone acetal_ A novel prenylated C6-C3 compound increasing choline acetyltransferase (ChAT) activity from Illicium tashiroi[J].Planta Med, 1997, 63(3):275.
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    [37] Ma SG, Tang WZ, Liu YX, et al. Prenylated C6-C3 compounds with molecular diversity from the roots of Illicium oligandrum[J]. Phytochemistry, 2011, 72(1):115.
    [38] Itoigawa M, Ito C, Tokuda H, et al. Cancer chemopreventive activity of phenylpropanoids and phytoquinoids from Illicium plants[J]. Cancer Letters, 2004, 214(2):165.
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  • 收稿日期:  2011-10-11
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八角属植物中的C6-C3类化合物及其药理活性研究进展

doi: 10.3969/j.issn.1006-0111.2012.01.003
    基金项目:  国家重大新药创制专项(2009ZX09502-021 与药效相关的中药质量评价关键技术成果研究).

摘要: 八角属植物中富含C6-C3类化合物,结构类型多样,有苯丙素类、木质素类和独特新颖的植物醌类,并具有较好的抗炎、神经营养、抗癌和抗氧化等活性,药用开发前景广阔。本文根据国内外文献报道,对该属植物C6-C3类化合物及其药理活性研究进展进行综述,为进一步研究开发该属植物提供参考。

English Abstract

邓华平, 孙蕾, 席忠新, 李霞, 陈程, 孙连娜. 八角属植物中的C6-C3类化合物及其药理活性研究进展[J]. 药学实践与服务, 2012, 30(1): 8-13. doi: 10.3969/j.issn.1006-0111.2012.01.003
引用本文: 邓华平, 孙蕾, 席忠新, 李霞, 陈程, 孙连娜. 八角属植物中的C6-C3类化合物及其药理活性研究进展[J]. 药学实践与服务, 2012, 30(1): 8-13. doi: 10.3969/j.issn.1006-0111.2012.01.003
DENG Hua-ping, SUN Lei, XI Zhong-xin, LI Xia, CHEN Cheng, SUN Lian-na. Progress on Chemical and pharmacological research of C6-C3 compounds in genus Illicium[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(1): 8-13. doi: 10.3969/j.issn.1006-0111.2012.01.003
Citation: DENG Hua-ping, SUN Lei, XI Zhong-xin, LI Xia, CHEN Cheng, SUN Lian-na. Progress on Chemical and pharmacological research of C6-C3 compounds in genus Illicium[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(1): 8-13. doi: 10.3969/j.issn.1006-0111.2012.01.003
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