Antibiotics application in intracoronary coronary stenting during perioperative period
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摘要: 目的 总结分析经皮冠脉支架置入(intracoronary coronary stenting, ICS)围手术期预防性使用抗菌药物情况,规范ICS围手术期抗菌药物使用和管理。 方法 采取回顾性调查方法,对2011年1~5月206例ICS手术患者,围手术期抗菌药物使用情况进行调查和分析。 结果 调查的206例ICS围手术期病例有7例未用抗菌药物,其余199例使用抗菌药物预防感染,使用率96.6%;预防用药以头霉素类为主,使用率60.86%,其次为一代和二代头孢菌素类,使用率分别为16.21%和13.04%Abstract: Objective To Sum up the situation of using antibiotics in intracoronary coronary stenting, and normalize the usage criterion and reinforce the management of antibiotics. Methods Retrospective survey method was used. 206 cases of patients who underwent cardiac intervention surgery between Jan., 2011 to May, 2011 were randomly selected for investigating and analyzing the usage of antibiotics. Results In the 260 cases, only 7 cases received no antibacterial treatment, while other 199 cases (96.6%) received prophylactic antibacterial treatment. The cephamycins was the predominant prophylactic antibiotics with the utility rate of 60.86%; the usage rate of first-generation and second-generation cephalosporins were 16.21% and 13.04% respectively; the usage rate of quinolone was 5.53%. All cases were medicated after surgery. The duration of prophylactic therapy spanned from 1d to 12 d, and the average antibacterial usage period was 3 d. Conclution The outstanding problems in prophylactic usage of antibiotics were the improper choice for the antibiotics, the improper choice for the medicinal usage occasion and the prolonged postoperative usage of antibiotics. It was urgent to intensify physicians' consciousness about rational use of antibiotics in intracoronary coronary stenting during perioperative period.
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