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选择性雌激素受体调节剂研究现状

丁浩,  杨帆,  蔡艺,  柴晓云,  吴秋业

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文章导航 > 药学实践与服务  > 2016 >  34(1): 1-4,55
丁浩, 杨帆, 蔡艺, 柴晓云, 吴秋业. 选择性雌激素受体调节剂研究现状[J]. 药学实践与服务, 2016, 34(1): 1-4,55. doi: 10.3969/j.issn.1006-0111.2016.01.001
引用本文: 丁浩, 杨帆, 蔡艺, 柴晓云, 吴秋业. 选择性雌激素受体调节剂研究现状[J]. 药学实践与服务, 2016, 34(1): 1-4,55. doi: 10.3969/j.issn.1006-0111.2016.01.001
shu
DING Hao, YANG Fan, CAI Yi, CHAI Xiaoyun, WU Qiuye. Research progress on the selective estrogen receptor modulators[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(1): 1-4,55. doi: 10.3969/j.issn.1006-0111.2016.01.001
Citation: DING Hao, YANG Fan, CAI Yi, CHAI Xiaoyun, WU Qiuye. Research progress on the selective estrogen receptor modulators[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(1): 1-4,55. doi: 10.3969/j.issn.1006-0111.2016.01.001
shu

选择性雌激素受体调节剂研究现状

doi: 10.3969/j.issn.1006-0111.2016.01.001
  • 1.

    第二军医大学药学院有机化学教研室, 上海 200433

  • 2.

    第二军医大学药学院有机化学教研室, 上海 200433;烟台大学药学院, 山东 烟台 264005

Research progress on the selective estrogen receptor modulators

  • 1.

    Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China

  • 2.

    Department of Organic Chemistry, School of Pharmacy, Second Military Medical University, Shanghai 200433, China;School of Pharmacy, Yantai University, Yantai 264005, China

  • 摘要: 乳腺癌已经成为危害女性健康的主要恶性肿瘤,选择性雌激素受体调节剂作为治疗乳腺癌的有效药物越来越受到人们的广泛关注。笔者对选择性雌激素受体调节剂的研究现状进行综述。
    Abstract: Breast cancer has become the main malignant tumors which pose a serious threat to women's health.Selective estrogen receptor modulators, which served as the effective drug treatment,have been attracting more attention. Present research progress on the selective estrogen receptor modulators was summarized in this paper.
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    [15] Jordan VC, McDaniel R, Agboke F, et al. The evolution of nonsteroidalantiestrogens to become selective estrogen receptor modulators[J]. Steroids, 2014, 90: 3-12.
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    [22] Top S, Vessi res A, Leclercq G, et al. Synthesis, biochemical properties and molecular modelling studies of organometallic specific estrogen receptor modulators (SERMs), the ferrocifens and hydroxyferrocifens: evidence for an antiproliferative effect of hydroxyferrocifens on both hormone-dependent and hormone-independent breast cancer cell lines[J]. Chemistry, 2003, 9(21): 5223-5236.
    [23] Plazuk D, Vessi res A, Hillard EA, et al. A[3]ferrocenophane polyphenol showing a remarkable antiproliferative activity on breast and prostate cancer cell lines[J]. J Med Chem, 2009, 52(15): 4964-4967.
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  • 收稿日期:  2014-10-13
  • 修回日期:  2015-06-05

选择性雌激素受体调节剂研究现状

doi: 10.3969/j.issn.1006-0111.2016.01.001
  • 1. 第二军医大学药学院有机化学教研室, 上海 200433
  • 2. 第二军医大学药学院有机化学教研室, 上海 200433;烟台大学药学院, 山东 烟台 264005
  • 收稿日期: 2014-10-13
  • 修回日期: 2015-06-05

摘要: 乳腺癌已经成为危害女性健康的主要恶性肿瘤,选择性雌激素受体调节剂作为治疗乳腺癌的有效药物越来越受到人们的广泛关注。笔者对选择性雌激素受体调节剂的研究现状进行综述。

English Abstract

丁浩, 杨帆, 蔡艺, 柴晓云, 吴秋业. 选择性雌激素受体调节剂研究现状[J]. 药学实践与服务, 2016, 34(1): 1-4,55. doi: 10.3969/j.issn.1006-0111.2016.01.001
引用本文: 丁浩, 杨帆, 蔡艺, 柴晓云, 吴秋业. 选择性雌激素受体调节剂研究现状[J]. 药学实践与服务, 2016, 34(1): 1-4,55. doi: 10.3969/j.issn.1006-0111.2016.01.001
shu
DING Hao, YANG Fan, CAI Yi, CHAI Xiaoyun, WU Qiuye. Research progress on the selective estrogen receptor modulators[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(1): 1-4,55. doi: 10.3969/j.issn.1006-0111.2016.01.001
Citation: DING Hao, YANG Fan, CAI Yi, CHAI Xiaoyun, WU Qiuye. Research progress on the selective estrogen receptor modulators[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(1): 1-4,55. doi: 10.3969/j.issn.1006-0111.2016.01.001
shu

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