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辐射所致肠道损伤中环氧酶作用的研究进展

陶玉龙,  杨宏,  陶霞

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陶玉龙, 杨宏, 陶霞. 辐射所致肠道损伤中环氧酶作用的研究进展[J]. 药学实践与服务, 2016, 34(3): 193-195. doi: 10.3969/j.issn.1006-0111.2016.03.001
引用本文: 陶玉龙, 杨宏, 陶霞. 辐射所致肠道损伤中环氧酶作用的研究进展[J]. 药学实践与服务, 2016, 34(3): 193-195. doi: 10.3969/j.issn.1006-0111.2016.03.001
shu
TAO Yulong, YANG Hong, TAO Xia. Role of cyclooxygenases in radiation enteropathy[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(3): 193-195. doi: 10.3969/j.issn.1006-0111.2016.03.001
Citation: TAO Yulong, YANG Hong, TAO Xia. Role of cyclooxygenases in radiation enteropathy[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(3): 193-195. doi: 10.3969/j.issn.1006-0111.2016.03.001
shu

辐射所致肠道损伤中环氧酶作用的研究进展

doi: 10.3969/j.issn.1006-0111.2016.03.001

  • 第二军医大学附属长征医院药学部, 上海 200003

基金项目: 上海市科学技术委员会科研计划项目(12401900704)

Role of cyclooxygenases in radiation enteropathy

  • Department of Pharmacy, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China

  • 摘要: 胃肠道对辐射高度敏感;防治辐射所致的胃肠道组织损伤一直是放射生物学领域探究的热点。以往研究表明,环氧酶对辐射引起的肠组织损伤有重要的保护作用。笔者就环氧酶在辐射所致肠道损伤中的作用及其机制做一综述。
    Abstract: Gastrointestinal tract is one of the most sensitive organs exposed to ionizing radiation. Radiation enteropathy is a hot topic in radiobiological field. Cumulative evidences demonstrated that cyclooxygenases (COXs) might contribute substantially to attenuating intestinal damage provoked by irradiation. The role of cyclooxygenases in radiation-induced intestinal damage was reviewed in this paper.
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    [2] Hauer-Jensen M, Denham JW, Andreyev HJ. Radiation enteropathy- -pathogenesis, treatment and prevention[J]. Nat Rev Gastroenterol Hepatol, 2014,11(8):470-479.
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  • 收稿日期:  2015-09-06
  • 修回日期:  2015-10-21

辐射所致肠道损伤中环氧酶作用的研究进展

doi: 10.3969/j.issn.1006-0111.2016.03.001
  • 第二军医大学附属长征医院药学部, 上海 200003
    • 基金项目:  上海市科学技术委员会科研计划项目(12401900704)
  • 收稿日期: 2015-09-06
  • 修回日期: 2015-10-21

摘要: 胃肠道对辐射高度敏感;防治辐射所致的胃肠道组织损伤一直是放射生物学领域探究的热点。以往研究表明,环氧酶对辐射引起的肠组织损伤有重要的保护作用。笔者就环氧酶在辐射所致肠道损伤中的作用及其机制做一综述。

English Abstract

陶玉龙, 杨宏, 陶霞. 辐射所致肠道损伤中环氧酶作用的研究进展[J]. 药学实践与服务, 2016, 34(3): 193-195. doi: 10.3969/j.issn.1006-0111.2016.03.001
引用本文: 陶玉龙, 杨宏, 陶霞. 辐射所致肠道损伤中环氧酶作用的研究进展[J]. 药学实践与服务, 2016, 34(3): 193-195. doi: 10.3969/j.issn.1006-0111.2016.03.001
shu
TAO Yulong, YANG Hong, TAO Xia. Role of cyclooxygenases in radiation enteropathy[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(3): 193-195. doi: 10.3969/j.issn.1006-0111.2016.03.001
Citation: TAO Yulong, YANG Hong, TAO Xia. Role of cyclooxygenases in radiation enteropathy[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(3): 193-195. doi: 10.3969/j.issn.1006-0111.2016.03.001
shu

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