右美托咪定用于神经阻滞的研究进展

陈琪; 刘兴; 刘红亮

doi:10.3969/j.issn.1006-0111.2018.04.001

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右美托咪定用于神经阻滞的研究进展

陈琪, 刘兴, 刘红亮

文章导航 > 药学实践与服务 > 2018 > 36(4): 289-292

陈琪, 刘兴, 刘红亮. 右美托咪定用于神经阻滞的研究进展[J]. 药学实践与服务, 2018, 36(4): 289-292. doi: 10.3969/j.issn.1006-0111.2018.04.001

引用本文:

陈琪, 刘兴, 刘红亮. 右美托咪定用于神经阻滞的研究进展[J]. 药学实践与服务, 2018, 36(4): 289-292. doi: 10.3969/j.issn.1006-0111.2018.04.001

CHEN Qi, LIU Xing, LIU Hongliang. Research progress of dexmedetomidine in nerve block[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(4): 289-292. doi: 10.3969/j.issn.1006-0111.2018.04.001

Citation:

CHEN Qi, LIU Xing, LIU Hongliang. Research progress of dexmedetomidine in nerve block[J]. Journal of Pharmaceutical Practice and Service, 2018, 36(4): 289-292. doi: 10.3969/j.issn.1006-0111.2018.04.001

右美托咪定用于神经阻滞的研究进展

doi: 10.3969/j.issn.1006-0111.2018.04.001

重庆大学附属肿瘤医院/重庆市肿瘤研究所/重市市肿瘤医院, 重庆 400030

基金项目: 重庆市科学技术委员会重点项目（cstc2017jcyj BX0043）

Research progress of dexmedetomidine in nerve block

Chongqing University Affiliated Cancer Hospital/Chongqing Cancer Institue/Chongqing Cancer Hospital, Chongqing 400030, China

摘要: 右美托咪定（Dex）是一种高选择性的α₂肾上腺素能受体激动剂，目前作为局麻药的辅助用药在神经阻滞中取得了良好的临床效果，可缩短局麻药的起效时间、延长镇痛时效并减少术后镇痛药的使用，同其他局麻药辅助药物相比，右美托咪定可提供更优的镇痛效果和时程，以及较少的不良反应。
- 右美托咪定 /
- 神经阻滞 /
- 安全性 /
- 机制
Abstract: Dexmedetomidine(Dex) is a specific alpha-2-adrenergic agonist which was widely used in nerve blocks as an adjuvant to local anesthetic(LA) in order to shortening the onset time, prolonging the analgesic effect and reducing the postoperative analgesic consumption.When compared with other adjuvant to LA,Dex was effective in providing better analgesia efficacy with fewer side effects.
- dexmedetomidine /
- nerve block /
- safety /
- mechanism

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