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急性高山病防治研究进展

熊娟,  鹿辉,  王荣,  贾正平

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文章导航 > 药学实践与服务  > 2017 >  35(2): 97-101
熊娟, 鹿辉, 王荣, 贾正平. 急性高山病防治研究进展[J]. 药学实践与服务, 2017, 35(2): 97-101. doi: 10.3969/j.issn.1006-0111.2017.02.001
引用本文: 熊娟, 鹿辉, 王荣, 贾正平. 急性高山病防治研究进展[J]. 药学实践与服务, 2017, 35(2): 97-101. doi: 10.3969/j.issn.1006-0111.2017.02.001
shu
XIONG Juan, LU Hui, WANG Rong, JIA Zhengping. Research progress on prevention and treatment of acute mountain sickness[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(2): 97-101. doi: 10.3969/j.issn.1006-0111.2017.02.001
Citation: XIONG Juan, LU Hui, WANG Rong, JIA Zhengping. Research progress on prevention and treatment of acute mountain sickness[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(2): 97-101. doi: 10.3969/j.issn.1006-0111.2017.02.001
shu

急性高山病防治研究进展

doi: 10.3969/j.issn.1006-0111.2017.02.001

  • 兰州总医院全军环境损伤防治重点实验室, 甘肃 兰州 730050

基金项目: 国家自然科学基金（81401552）

Research progress on prevention and treatment of acute mountain sickness

  • Key Laboratory of the Plateau of Environmental Damage Control, Lanzhou General Hospital, Lanzhou 730050, China

  • 摘要: 高海拔未习服人群快速进入高海拔地区易患急性高山病（acute mountain sickness，AMS）。AMS是一种以头痛为主要症状并伴有肠胃不适、眩晕、疲劳和失眠等症状的自限性疾病。虽然对AMS已经开展了大量研究，但业内对其病理机制以及有效防治等方面的认识还非常有限。深入认识AMS的诊断方法、危险因素和病理生理机制，对提出针对AMS有效的防治措施十分重要。本文基于课题组的前期研究和相关文献，较为系统地综述AMS的临床诊断、危险因素、病理生理机制和防治措施。
    Abstract: Acute mountain sickness (AMS) is a self-limiting medical condition characterized by headache, nausea, fatigue, dizziness, and insomnia. AMS usually occurs after rapid ascent to high altitudes in non-altitude acclimatized individuals. Extensive studies have been done on AMS, but knowledge on the mechanism, prevention and treatment are still limited. It will help the prevention and treatment of AMS with deep understanding of its risk factors and mechanisms. In this article, we systematically reviewed the diagnosis, risk factors, developing mechanisms, preventions and treatments of AMS.
  • [1] Bartsch P,Swenson ER. Clinical practice:Acute high-altitude illnesses[J]. N Engl J Med,2013,368(24):2294-2302.
    [2] Gonggalanzi,Labasangzhu,Nafstad P,et al. Acute mountain sickness among tourists visiting the high-altitude city of Lhasa at 3658 m above sea level:a cross-sectional study[J]. Arch Public Health,2016,74(1):1-7.
    [3] Fruhauf A,Burtscher M,Pocecco E,et al. Subjective assessment of acute mountain sickness:investigating the relationship between the Lake Louise Self-Report,a visual analogue scale and psychological well-being scales[J]. Springerplus,2016,5(1):1646.
    [4] Wu J,Chen Y,Luo Y. Evaluation of the visual analog score (VAS) to assess acute mountain sickness (AMS) in a hypobaric chamber[J]. PLoS One,2014,9(11):e113376.
    [5] Fiore DC,Hall S,Shoja P. Altitude illness:risk factors,prevention,presentation,and treatment[J]. Am Fam Physician,2010,82(9):1103-1110.
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    [9] Bailey DM,Roukens R,Knauth M,et al. Free radical-mediated damage to barrier function is not associated with altered brain morphology in high-altitude headache[J]. J Cereb Blood Flow Metab,2006,26(1):99-111.
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    [11] Mairer K,Gobel M,Defrancesco M,et al. MRI evidence:acute mountain sickness is not associated with cerebral edema formation during simulated high altitude[J]. PLoS One,2012,7(11):e50334.
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    [15] Julian CG,Subudhi AW,Hill RC,et al. Exploratory proteomic analysis of hypobaric hypoxia and acute mountain sickness in humans[J]. J Appl Physiol,2014,116(7):937-944.
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出版历程
  • 收稿日期:  2016-08-30
  • 修回日期:  2016-11-07

急性高山病防治研究进展

doi: 10.3969/j.issn.1006-0111.2017.02.001
  • 兰州总医院全军环境损伤防治重点实验室, 甘肃 兰州 730050
    • 基金项目:  国家自然科学基金（81401552）
  • 收稿日期: 2016-08-30
  • 修回日期: 2016-11-07

摘要: 高海拔未习服人群快速进入高海拔地区易患急性高山病（acute mountain sickness，AMS）。AMS是一种以头痛为主要症状并伴有肠胃不适、眩晕、疲劳和失眠等症状的自限性疾病。虽然对AMS已经开展了大量研究，但业内对其病理机制以及有效防治等方面的认识还非常有限。深入认识AMS的诊断方法、危险因素和病理生理机制，对提出针对AMS有效的防治措施十分重要。本文基于课题组的前期研究和相关文献，较为系统地综述AMS的临床诊断、危险因素、病理生理机制和防治措施。

English Abstract

熊娟, 鹿辉, 王荣, 贾正平. 急性高山病防治研究进展[J]. 药学实践与服务, 2017, 35(2): 97-101. doi: 10.3969/j.issn.1006-0111.2017.02.001
引用本文: 熊娟, 鹿辉, 王荣, 贾正平. 急性高山病防治研究进展[J]. 药学实践与服务, 2017, 35(2): 97-101. doi: 10.3969/j.issn.1006-0111.2017.02.001
shu
XIONG Juan, LU Hui, WANG Rong, JIA Zhengping. Research progress on prevention and treatment of acute mountain sickness[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(2): 97-101. doi: 10.3969/j.issn.1006-0111.2017.02.001
Citation: XIONG Juan, LU Hui, WANG Rong, JIA Zhengping. Research progress on prevention and treatment of acute mountain sickness[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(2): 97-101. doi: 10.3969/j.issn.1006-0111.2017.02.001
shu

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