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Volume 30 Issue 5
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2012  >  30(5): 348-350

ZENG Chao. Optimization of the matrix formulation of Huoxuetongluo cataplasmata by orthogonal design[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(5): 348-350. doi: 10.3969/j.issn.1006-0111.2012.05.008
Citation: ZENG Chao. Optimization of the matrix formulation of Huoxuetongluo cataplasmata by orthogonal design[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(5): 348-350. doi: 10.3969/j.issn.1006-0111.2012.05.008
shu

Optimization of the matrix formulation of Huoxuetongluo cataplasmata by orthogonal design

doi: 10.3969/j.issn.1006-0111.2012.05.008

  • Third Hospital Affiliated to Zhejiang University of TCM, Hangzhou 310053, China

  • Received Date: 2012-02-18
  • Rev Recd Date: 2012-03-27
  • Objective To optimize the matrix formulation of Huoxuetongluo cataplasmata. Methods The optimal preparation was selected by L16 (45) orthogonal design. The adhering potential, fissility, ability to spread out, homogeneity, ability pasting to skin and recontourity were used as indexes. Results The optimal matrix formulation was water:glycerine:gelatin:sodium polyacrylate:sodium carboxymethycellulose:polyvinylpyrrolidone=6.0:4.0:1.6:0.4:0.3. Conclusion The optimal matrix formulation was practical and economical which was compatible with Huoxuetongluo medicine.
  • [1] 于晓佳, 贾伟. 正交试验法优选金铃子巴布剂基质的研究[J]. 药物研究, 2008, 16:39.
    [2] 左亚杰, 林新文.伤速康巴布剂的基质配方研究[J]. 中国现代药物应用, 2008, 5(2):25.
    [3] 中国药典2005版.一部[S]. 2005:附录Ⅱ.
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Optimization of the matrix formulation of Huoxuetongluo cataplasmata by orthogonal design

doi: 10.3969/j.issn.1006-0111.2012.05.008
  • Third Hospital Affiliated to Zhejiang University of TCM, Hangzhou 310053, China
  • Received Date: 2012-02-18
  • Rev Recd Date: 2012-03-27

Abstract: Objective To optimize the matrix formulation of Huoxuetongluo cataplasmata. Methods The optimal preparation was selected by L16 (45) orthogonal design. The adhering potential, fissility, ability to spread out, homogeneity, ability pasting to skin and recontourity were used as indexes. Results The optimal matrix formulation was water:glycerine:gelatin:sodium polyacrylate:sodium carboxymethycellulose:polyvinylpyrrolidone=6.0:4.0:1.6:0.4:0.3. Conclusion The optimal matrix formulation was practical and economical which was compatible with Huoxuetongluo medicine.

ZENG Chao. Optimization of the matrix formulation of Huoxuetongluo cataplasmata by orthogonal design[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(5): 348-350. doi: 10.3969/j.issn.1006-0111.2012.05.008
Citation: ZENG Chao. Optimization of the matrix formulation of Huoxuetongluo cataplasmata by orthogonal design[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(5): 348-350. doi: 10.3969/j.issn.1006-0111.2012.05.008
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