2012 Vol. 30, No. 5
Display Method:
2012, 30(5): 321-325.
doi: 10.3969/j.issn.1006-0111.2012.05.001
Abstract:
With the continuous development of biotechnology technology, microbial transformation gradually was applied to the study of natural products. The specific effective reactions, mild reaction conditions and high yield of the microbial transformation we...
With the continuous development of biotechnology technology, microbial transformation gradually was applied to the study of natural products. The specific effective reactions, mild reaction conditions and high yield of the microbial transformation we...
2012, 30(5): 326-330,343.
doi: 10.3969/j.issn.1006-0111.2012.05.002
Abstract:
Pulsatile drug delivery system developed quickly with the further study of chronobiology and chronopharmacology, which controled drug release and dosage by the method of formulation, and could coordinate the change of physiological rhythm, furthermor...
Pulsatile drug delivery system developed quickly with the further study of chronobiology and chronopharmacology, which controled drug release and dosage by the method of formulation, and could coordinate the change of physiological rhythm, furthermor...
2012, 30(5): 331-333,368.
doi: 10.3969/j.issn.1006-0111.2012.05.003
Abstract:
Objective To review the latest research progress of the solid lipid nano-particle. Methods Domestic and foreign representative literature information of solid lipid nano-particles and its application were analyzed and summarized. Results Many ki...
Objective To review the latest research progress of the solid lipid nano-particle. Methods Domestic and foreign representative literature information of solid lipid nano-particles and its application were analyzed and summarized. Results Many ki...
2012, 30(5): 334-335,360.
doi: 10.3969/j.issn.1006-0111.2012.05.004
Abstract:
Naphthoquinones were widely distributed in some traditional medicine plants. Shikonin, juglone, lawsone, plumbagin were naturally occurring naphthoquinones of the traditional medicine plant. The research results indicated that naphthoquinones and nap...
Naphthoquinones were widely distributed in some traditional medicine plants. Shikonin, juglone, lawsone, plumbagin were naturally occurring naphthoquinones of the traditional medicine plant. The research results indicated that naphthoquinones and nap...
2012, 30(5): 336-339.
doi: 10.3969/j.issn.1006-0111.2012.05.005
Abstract:
Lopinavir was widely used as a second generation protease inhibitor in AIDS therapy, which was quickly metabolized by CYP3A4. For individual variance might lead to different metabolism, it was important to study the pharmacokinetic parameters of lopi...
Lopinavir was widely used as a second generation protease inhibitor in AIDS therapy, which was quickly metabolized by CYP3A4. For individual variance might lead to different metabolism, it was important to study the pharmacokinetic parameters of lopi...
2012, 30(5): 340-343.
doi: 10.3969/j.issn.1006-0111.2012.05.006
Abstract:
To build a effective method to evaluate the safety and efficacy of TMC was a main problem in TMC quality control system.The TMC quality affected the clinical curative effect directely, which was the bottle neck of the TMC modernization according to t...
To build a effective method to evaluate the safety and efficacy of TMC was a main problem in TMC quality control system.The TMC quality affected the clinical curative effect directely, which was the bottle neck of the TMC modernization according to t...
2012, 30(5): 344-347.
doi: 10.3969/j.issn.1006-0111.2012.05.007
Abstract:
Objective To synthesize the geometric isomer of (E)-1-((4-(2,4-difluorophenyl)-2-(4-fluorostyryl)-1,3-dioxolan-4-yl)methyl)-1H-1,2,4-triazole, determine their structures by XRD and evaluate their antifungal activities in vitro. Methods The target c...
Objective To synthesize the geometric isomer of (E)-1-((4-(2,4-difluorophenyl)-2-(4-fluorostyryl)-1,3-dioxolan-4-yl)methyl)-1H-1,2,4-triazole, determine their structures by XRD and evaluate their antifungal activities in vitro. Methods The target c...
2012, 30(5): 348-350.
doi: 10.3969/j.issn.1006-0111.2012.05.008
Abstract:
Objective To optimize the matrix formulation of Huoxuetongluo cataplasmata. Methods The optimal preparation was selected by L16 (45) orthogonal design. The adhering potential, fissility, ability to spread out, homogeneity, ability pasting to skin a...
Objective To optimize the matrix formulation of Huoxuetongluo cataplasmata. Methods The optimal preparation was selected by L16 (45) orthogonal design. The adhering potential, fissility, ability to spread out, homogeneity, ability pasting to skin a...
2012, 30(5): 351-352,386.
doi: 10.3969/j.issn.1006-0111.2012.05.009
Abstract:
To establish a HPLC fingerprint method for Semen Sojae Preparatumto quality control. Methods HPLC analysis was performed on a Diamonsil C18 column (250 mm×4.6 mm,5 μm),the mobile phase was used in gradient elution consisted of methanol-water(3% ace...
To establish a HPLC fingerprint method for Semen Sojae Preparatumto quality control. Methods HPLC analysis was performed on a Diamonsil C18 column (250 mm×4.6 mm,5 μm),the mobile phase was used in gradient elution consisted of methanol-water(3% ace...
2012, 30(5): 353-356.
doi: 10.3969/j.issn.1006-0111.2012.05.010
Abstract:
Objective To analyze the chemical components of the essential oil from Fuzhengpingxiao capsule by GC-MS. Methods The essential oil was extracted by steam distillation,the chemical components of the essential oil were detected by GC-MS.Peaks and the...
Objective To analyze the chemical components of the essential oil from Fuzhengpingxiao capsule by GC-MS. Methods The essential oil was extracted by steam distillation,the chemical components of the essential oil were detected by GC-MS.Peaks and the...
2012, 30(5): 357-360.
doi: 10.3969/j.issn.1006-0111.2012.05.011
Abstract:
Objective To study the effect of Fructus Mume(FM) on superoxide dismutase(SOD) activity and malondialdehyde(MDA) content in ulcerative colitis in mouse. Methods The mouse model of ulcerative colitis was set up by giving 3% dextran sulfate sodium(D...
Objective To study the effect of Fructus Mume(FM) on superoxide dismutase(SOD) activity and malondialdehyde(MDA) content in ulcerative colitis in mouse. Methods The mouse model of ulcerative colitis was set up by giving 3% dextran sulfate sodium(D...
2012, 30(5): 361-364.
doi: 10.3969/j.issn.1006-0111.2012.05.012
Abstract:
Objective To analyze the lever and dynamics of systemic inflammatory response syndrome in the patients after hepatectomy, so as to provide some references for the treatment of preventing SIRS and decrease of infection rate. Methods The occurrence ...
Objective To analyze the lever and dynamics of systemic inflammatory response syndrome in the patients after hepatectomy, so as to provide some references for the treatment of preventing SIRS and decrease of infection rate. Methods The occurrence ...
2012, 30(5): 365-368.
doi: 10.3969/j.issn.1006-0111.2012.05.013
Abstract:
Objective To study the stability of compatibility of carbazochrome sodium sulfonate with four different transfusions for 6 hours at room temperature. Methods The content and related substances of carbazochrome sodium for sulfonate injection in four...
Objective To study the stability of compatibility of carbazochrome sodium sulfonate with four different transfusions for 6 hours at room temperature. Methods The content and related substances of carbazochrome sodium for sulfonate injection in four...
2012, 30(5): 369-371,375.
doi: 10.3969/j.issn.1006-0111.2012.05.014
Abstract:
Objective To prepare Garcinia glycosides sustained-release tables and study their in vitro release characteristics. Methods Garcinia glycosides sustained-release tablets were prepared by hydroxypropylmethyl cellulose (HPMC) as gel matrix material ...
Objective To prepare Garcinia glycosides sustained-release tables and study their in vitro release characteristics. Methods Garcinia glycosides sustained-release tablets were prepared by hydroxypropylmethyl cellulose (HPMC) as gel matrix material ...
2012, 30(5): 372-375.
doi: 10.3969/j.issn.1006-0111.2012.05.015
Abstract:
Objective To determine Sparfloxacin concentrations in human plasma and study the pharmacokinetics and relative bioavailability of Sparfloxacin for Suspension. Methods A single dose reference and test was given to 20 healthy volunteers in a randomi...
Objective To determine Sparfloxacin concentrations in human plasma and study the pharmacokinetics and relative bioavailability of Sparfloxacin for Suspension. Methods A single dose reference and test was given to 20 healthy volunteers in a randomi...
2012, 30(5): 376-377,383.
doi: 10.3969/j.issn.1006-0111.2012.05.016
Abstract:
Objective To establish a HPLC method for tetrahydropalmatine in Lianlian capsule. Method The determination method of Lianlian capsule was carried out by HPLC, which quantitative index was represented with tetrahydropalmatine. Result The calibration ...
Objective To establish a HPLC method for tetrahydropalmatine in Lianlian capsule. Method The determination method of Lianlian capsule was carried out by HPLC, which quantitative index was represented with tetrahydropalmatine. Result The calibration ...
2012, 30(5): 378-379,389.
doi: 10.3969/j.issn.1006-0111.2012.05.017
Abstract:
To established the HPLC method for simultaneously determination of quercitin and quercitrin in Polygonum hydropiper Linn. Methods A VertiSep GES C18 (250 mm ×4.6 mm,5.0 μm)column was adopted with a mobile phase of acetonitrile-0.1% formic acid wate...
To established the HPLC method for simultaneously determination of quercitin and quercitrin in Polygonum hydropiper Linn. Methods A VertiSep GES C18 (250 mm ×4.6 mm,5.0 μm)column was adopted with a mobile phase of acetonitrile-0.1% formic acid wate...
2012, 30(5): 380-383.
doi: 10.3969/j.issn.1006-0111.2012.05.018
Abstract:
Objective To analyze several adverse drug reaction monitoring methods in home and aboard. Methods Literature analysis and system analysis method were used to illustrate a series of calculation methods in signal extraction of adverse drug reaction. ...
Objective To analyze several adverse drug reaction monitoring methods in home and aboard. Methods Literature analysis and system analysis method were used to illustrate a series of calculation methods in signal extraction of adverse drug reaction. ...
2012, 30(5): 384-386.
doi: 10.3969/j.issn.1006-0111.2012.05.019
Abstract:
Objective To grasp current status of irrational prescriptions in outpatient department of our hospital and to promote clinically rational use of drugs. Method Based on the irrational prescription criteria taken from management of prescriptions and s...
Objective To grasp current status of irrational prescriptions in outpatient department of our hospital and to promote clinically rational use of drugs. Method Based on the irrational prescription criteria taken from management of prescriptions and s...
2012, 30(5): 387-389.
doi: 10.3969/j.issn.1006-0111.2012.05.020
Abstract:
Objective To analyse the quality issues of preparation in Jinan Military Region and improve the quality of preparation in medical institutions. Methods According to the 2007~2011 inspection records and the test results, the main quality problems o...
Objective To analyse the quality issues of preparation in Jinan Military Region and improve the quality of preparation in medical institutions. Methods According to the 2007~2011 inspection records and the test results, the main quality problems o...
2012, 30(5): 390-391,398.
doi: 10.3969/j.issn.1006-0111.2012.05.021
Abstract:
The practice of spectrum analysis experiment teaching based on comprehensive structure identification was to simulate the procedure of elucidating structure by spectroscopy methods, including UV, IR, NMR and MS in new drug research, which could help ...
The practice of spectrum analysis experiment teaching based on comprehensive structure identification was to simulate the procedure of elucidating structure by spectroscopy methods, including UV, IR, NMR and MS in new drug research, which could help ...
2012, 30(5): 392-393,400.
doi: 10.3969/j.issn.1006-0111.2012.05.022
Abstract:
Pharmacy was a comprehensive and inter-disciplinary course. The comprehensive and designing experiment of pharmacy based on inter-discipline was set up in the pharmacy experiments relying on experimental teaching center, which not only improve the st...
Pharmacy was a comprehensive and inter-disciplinary course. The comprehensive and designing experiment of pharmacy based on inter-discipline was set up in the pharmacy experiments relying on experimental teaching center, which not only improve the st...
2012, 30(5): 394-398.
doi: 10.3969/j.issn.1006-0111.2012.05.023
Abstract:
Objective During internship of pharmacy student, multidisciplinary pharmacy experiment about preparation of Aspirin tablet was performed. Methods Three in group of the pharmacy students completed literature review and experimental design. the aspi...
Objective During internship of pharmacy student, multidisciplinary pharmacy experiment about preparation of Aspirin tablet was performed. Methods Three in group of the pharmacy students completed literature review and experimental design. the aspi...
2012, 30(5): 399-400.
doi: 10.3969/j.issn.1006-0111.2012.05.024
Abstract:
The pharmacy administration teaching for the pre-selected medical noncommissioned officers was a new task and there was no experience to follow. Based on the author's own practical experience, systematic conclusion from the curriculum designation, th...
The pharmacy administration teaching for the pre-selected medical noncommissioned officers was a new task and there was no experience to follow. Based on the author's own practical experience, systematic conclusion from the curriculum designation, th...
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