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Volume 30 Issue 5
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2012  >  30(5): 361-364

GONG Chun-guia, WANG Binb, ZHAN Qib, JIN Rou-nanb, JIANG Yun-xiab, YAN Jian-jun. Analysis of incidence and influencing factors of systemic inflammatory response syndrome after hepatectomy[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(5): 361-364. doi: 10.3969/j.issn.1006-0111.2012.05.012
Citation: GONG Chun-guia, WANG Binb, ZHAN Qib, JIN Rou-nanb, JIANG Yun-xiab, YAN Jian-jun. Analysis of incidence and influencing factors of systemic inflammatory response syndrome after hepatectomy[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(5): 361-364. doi: 10.3969/j.issn.1006-0111.2012.05.012
shu

Analysis of incidence and influencing factors of systemic inflammatory response syndrome after hepatectomy

doi: 10.3969/j.issn.1006-0111.2012.05.012
  • 1.

    Eastern Hepatobiliary Surgery Hospital, Second Military Medical University Department of instrument, Shanghai 200438, China

  • 2.

    Eastern Hepatobiliary Surgery Hospital, Department of Phamacy, Shanghai 200438, China

  • 3.

    Eastern Hepatobiliary Surgery Hospital, epartment of hepatic surgery, Shanghai 200438, China

  • Received Date: 2012-02-10
  • Rev Recd Date: 2012-04-27
  • Objective To analyze the lever and dynamics of systemic inflammatory response syndrome in the patients after hepatectomy, so as to provide some references for the treatment of preventing SIRS and decrease of infection rate. Methods The occurrence of SIRS on patients of hepatectomy in single treatment group nearly 4 years were surveyed byretrospective analysis. Results The rate of SIRS was 96.98% in the 232 cases of hepatectomy. SIRS severity occurred gradually declined with the extension of treatment after surgery. The SIRS Peak after surgery was correlated with maximum tumor diameter and cirrhosis of liver on primary liver cancer group. There was no comparability between the SIRS Score and antibiotics combined with double or triple. Conclusions The application of SIRS Score and early detection of SIRS was a certain clinical significance to improve the cure rate of liver resection and reduce infection rates.
  • [1] 吴孟超,陈汉,姚晓平,等.原发性肝癌的外科治疗[J].中华外科杂志,1996,46(12):47.
    [2] Cavaillon JM,Annane D.Compartmentalization of the inflammatory response in sepsis and SIRS[J].J Endotoxin Res,2006,12(3):151.
    [3] Bone RC, Balk RA, Cerra FB,et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The American College of Chest Physicians Society of Critioal Care Medicine comsensus Conference[J].Chest,1992,101(6):1644.
    [4] Wittmann DH,Schein M,Condon RE.Management of secondary peritonitis[J].Ann Surg,1996,224(1):10.
    [5] 陈自平,卢圣爱,徐昌青,等.重型病毒性肝炎患者医院感染及其预防[J]. 中华医院感染学杂志,2005,15(7):790.
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Analysis of incidence and influencing factors of systemic inflammatory response syndrome after hepatectomy

doi: 10.3969/j.issn.1006-0111.2012.05.012
  • 1. Eastern Hepatobiliary Surgery Hospital, Second Military Medical University Department of instrument, Shanghai 200438, China
  • 2. Eastern Hepatobiliary Surgery Hospital, Department of Phamacy, Shanghai 200438, China
  • 3. Eastern Hepatobiliary Surgery Hospital, epartment of hepatic surgery, Shanghai 200438, China
  • Received Date: 2012-02-10
  • Rev Recd Date: 2012-04-27

Abstract: Objective To analyze the lever and dynamics of systemic inflammatory response syndrome in the patients after hepatectomy, so as to provide some references for the treatment of preventing SIRS and decrease of infection rate. Methods The occurrence of SIRS on patients of hepatectomy in single treatment group nearly 4 years were surveyed byretrospective analysis. Results The rate of SIRS was 96.98% in the 232 cases of hepatectomy. SIRS severity occurred gradually declined with the extension of treatment after surgery. The SIRS Peak after surgery was correlated with maximum tumor diameter and cirrhosis of liver on primary liver cancer group. There was no comparability between the SIRS Score and antibiotics combined with double or triple. Conclusions The application of SIRS Score and early detection of SIRS was a certain clinical significance to improve the cure rate of liver resection and reduce infection rates.

GONG Chun-guia, WANG Binb, ZHAN Qib, JIN Rou-nanb, JIANG Yun-xiab, YAN Jian-jun. Analysis of incidence and influencing factors of systemic inflammatory response syndrome after hepatectomy[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(5): 361-364. doi: 10.3969/j.issn.1006-0111.2012.05.012
Citation: GONG Chun-guia, WANG Binb, ZHAN Qib, JIN Rou-nanb, JIANG Yun-xiab, YAN Jian-jun. Analysis of incidence and influencing factors of systemic inflammatory response syndrome after hepatectomy[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(5): 361-364. doi: 10.3969/j.issn.1006-0111.2012.05.012
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