Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code
x Close Forever Close
Volume 30 Issue 5
. 
Turn off MathJax
Article Contents
Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2012  >  30(5): 369-371,375

CHEN Ye, WANG Yang, LIU Zhong-chen, LI Wen-jun, DENG Jing-jing, XU Li-feng. Preparation and in vitro release of Garcinia glycosides sustained-release tablets[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(5): 369-371,375. doi: 10.3969/j.issn.1006-0111.2012.05.014
Citation: CHEN Ye, WANG Yang, LIU Zhong-chen, LI Wen-jun, DENG Jing-jing, XU Li-feng. Preparation and in vitro release of Garcinia glycosides sustained-release tablets[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(5): 369-371,375. doi: 10.3969/j.issn.1006-0111.2012.05.014
shu

Preparation and in vitro release of Garcinia glycosides sustained-release tablets

doi: 10.3969/j.issn.1006-0111.2012.05.014

  • School of Pharmacy, Liaoning University, Shenyang 110036, China

  • Received Date: 2012-02-06
  • Rev Recd Date: 2012-05-22
  • Objective To prepare Garcinia glycosides sustained-release tables and study their in vitro release characteristics. Methods Garcinia glycosides sustained-release tablets were prepared by hydroxypropylmethyl cellulose (HPMC) as gel matrix material and ethyl cellulose (EC) as skeleton material. Factors influencing the release rate of Garcinia glycosides from the sustained-release tablets, such as pH of release medium, skeleton material and amount of HPMC, porogen of type and amount, and tabletting pressure, were studied. Results Garcinia glycosides release rate was controlled obviously by the specifications and amount of skeleton material and porogen type. While the influence of pH, speed and tabletting pressure had certain influences to the release rate. Conclusion The selected formulation of Garcinia glycosides sustained-release tablets was reasonable with good controllability and reproducibility.
  • [1] 徐利锋.藤黄酸苷衍生物和类似物及其制备方法和用途[P].中国专利,101289482A,2008-10-22.
    [2] Zong L,Chen LL,Zhang Y. Studies on nitrendipine sustained-release tablets and in vitro release se characteristics[J]. J China Pharm Univ,2004,35 (6):503.
    [3] 中国药典2010版.二部[S]. 2010:附录,87.
    [4] 颜耀东.缓释控释制剂的设计与开发[M]. 北京:中国医药科技出版社, 2006:68
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索
Get Citation
PDF
XML

Article Metrics

Article views(4810) PDF downloads(296) Cited by()

Related
Proportional views

Preparation and in vitro release of Garcinia glycosides sustained-release tablets

doi: 10.3969/j.issn.1006-0111.2012.05.014
  • School of Pharmacy, Liaoning University, Shenyang 110036, China
  • Received Date: 2012-02-06
  • Rev Recd Date: 2012-05-22

Abstract: Objective To prepare Garcinia glycosides sustained-release tables and study their in vitro release characteristics. Methods Garcinia glycosides sustained-release tablets were prepared by hydroxypropylmethyl cellulose (HPMC) as gel matrix material and ethyl cellulose (EC) as skeleton material. Factors influencing the release rate of Garcinia glycosides from the sustained-release tablets, such as pH of release medium, skeleton material and amount of HPMC, porogen of type and amount, and tabletting pressure, were studied. Results Garcinia glycosides release rate was controlled obviously by the specifications and amount of skeleton material and porogen type. While the influence of pH, speed and tabletting pressure had certain influences to the release rate. Conclusion The selected formulation of Garcinia glycosides sustained-release tablets was reasonable with good controllability and reproducibility.

CHEN Ye, WANG Yang, LIU Zhong-chen, LI Wen-jun, DENG Jing-jing, XU Li-feng. Preparation and in vitro release of Garcinia glycosides sustained-release tablets[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(5): 369-371,375. doi: 10.3969/j.issn.1006-0111.2012.05.014
Citation: CHEN Ye, WANG Yang, LIU Zhong-chen, LI Wen-jun, DENG Jing-jing, XU Li-feng. Preparation and in vitro release of Garcinia glycosides sustained-release tablets[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(5): 369-371,375. doi: 10.3969/j.issn.1006-0111.2012.05.014
shu

    HTML

Reference (4)

Catalog

    版权所有：《药学实践与服务》编辑委员会

    Supervisor & Sponsors: Address: No 325 Guohe Road, ShanghaiPost Code: 200433

    Tel: （021）81871324,81871397 E-mail: yxsjzzs@163.com

    网站备案号 沪ICP备05003363号-1

    Supported by: Beijing Renhe Information Technology Co., Ltd.  

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return