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Volume 31 Issue 1
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2013  >  31(1): 32-34

YAN Jun, XUAN Wei-dong, BIAN Jun. Study on clarification process of Bairui oral liquid[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(1): 32-34. doi: 10.3969/j.issn.1006-0111.2013.01.009
Citation: YAN Jun, XUAN Wei-dong, BIAN Jun. Study on clarification process of Bairui oral liquid[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(1): 32-34. doi: 10.3969/j.issn.1006-0111.2013.01.009
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Study on clarification process of Bairui oral liquid

doi: 10.3969/j.issn.1006-0111.2013.01.009
  • 1.

    The 411th Hospital of PLA, Shanghai 200434, China;Jiangxi University of Traditional Chinese Medicine, Nanchang 333004, China

  • 2.

    The 411th Hospital of PLA, Shanghai 200434, China

  • Received Date: 2011-11-29
  • Rev Recd Date: 2012-10-17
  • Objective To establish a optimum clarification process of Bairui oral liquid with new ZTCI+1-Ⅱ natural clarifying agents. Methods The effects on clarification of Bairui oral liquid were evaluated based on the factors such as adding sequence, added amount and clarification time of ZTCl+1-Ⅱ clarifiers A and B. The contents of astragalin and total flavones were determinate by the HPLC and UV methods respectively to evaluate the removing activities of ZTCl+1-Ⅱon active components. Results The selected clarification process conditions were: adding 20% percentage of each components of ZTCl+1-Ⅱto the condensed herb extract solution, the adding sequence was clarifiers B before clarifiers A, and the clarification time was 12 h, respectively. Conclusion The contents of astragalin and total flavones were not decreased by clarification process, ZTCl+1-Ⅱ could be used as the removing impurity of Bairui oral liquid.
  • [1] 国家中医药管理局,中华本草编委会.中华本草[M].上海: 上海科技出版社,1999, 2: 595.
    [2] 宣伟东,唐大海,卞 俊,等. 百蕊草对阿霉素肾病大鼠治疗作用的实验研究[J].药学实践杂志,2012,30(6):443.
    [3] 祝志贤,梁秋文,程婉玲. ZTC1+1天然澄清剂在清开灵口服液制备工艺中的应用[J].药学实践杂志,2009,27(4): 274.
    [4] 刘 洋,邓玉林,禹玉洪,等. RP-HPLC测定百蕊草中紫云英苷的含量[J].中国中药杂志, 2006, 31(21): 1766.
    [5] 王 峥,李绍顺.百蕊草药材及其制剂中总黄酮的含量测定[J].中成药, 2007, 29(1): 138.
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Study on clarification process of Bairui oral liquid

doi: 10.3969/j.issn.1006-0111.2013.01.009
  • 1. The 411th Hospital of PLA, Shanghai 200434, China;Jiangxi University of Traditional Chinese Medicine, Nanchang 333004, China
  • 2. The 411th Hospital of PLA, Shanghai 200434, China
  • Received Date: 2011-11-29
  • Rev Recd Date: 2012-10-17

Abstract: Objective To establish a optimum clarification process of Bairui oral liquid with new ZTCI+1-Ⅱ natural clarifying agents. Methods The effects on clarification of Bairui oral liquid were evaluated based on the factors such as adding sequence, added amount and clarification time of ZTCl+1-Ⅱ clarifiers A and B. The contents of astragalin and total flavones were determinate by the HPLC and UV methods respectively to evaluate the removing activities of ZTCl+1-Ⅱon active components. Results The selected clarification process conditions were: adding 20% percentage of each components of ZTCl+1-Ⅱto the condensed herb extract solution, the adding sequence was clarifiers B before clarifiers A, and the clarification time was 12 h, respectively. Conclusion The contents of astragalin and total flavones were not decreased by clarification process, ZTCl+1-Ⅱ could be used as the removing impurity of Bairui oral liquid.

YAN Jun, XUAN Wei-dong, BIAN Jun. Study on clarification process of Bairui oral liquid[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(1): 32-34. doi: 10.3969/j.issn.1006-0111.2013.01.009
Citation: YAN Jun, XUAN Wei-dong, BIAN Jun. Study on clarification process of Bairui oral liquid[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(1): 32-34. doi: 10.3969/j.issn.1006-0111.2013.01.009
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