2013 Vol. 31, No. 1
Display Method:
2013, 31(1): 1-4,74.
doi: 10.3969/j.issn.1006-0111.2013.01.001
Abstract:
The principles and applications of ICA methods were reviewed. Firstly, a summary of the background and development prospects of the ICA were described, the definition, basic principles, and ten algorithms of ICA were briefly introduced,and then the p...
The principles and applications of ICA methods were reviewed. Firstly, a summary of the background and development prospects of the ICA were described, the definition, basic principles, and ten algorithms of ICA were briefly introduced,and then the p...
2013, 31(1): 5-10,71.
doi: 10.3969/j.issn.1006-0111.2013.01.002
Abstract:
Benzofuran derivatives were a series of attracting heterocyclic compounds with a variety of biological activity. Based on the recently published literatures, these derivatives had shown antitumor, antioxidant, calcium influx blockade, angiotensin II ...
Benzofuran derivatives were a series of attracting heterocyclic compounds with a variety of biological activity. Based on the recently published literatures, these derivatives had shown antitumor, antioxidant, calcium influx blockade, angiotensin II ...
2013, 31(1): 11-13,31.
doi: 10.3969/j.issn.1006-0111.2013.01.003
Abstract:
The integrity and function of the endothelium played a key role in the prevention of cardiovascular diseases (CVDs). The maintenance of normal endothelial function not only depended on pre-existing endothelial cells, but also included the recruitment...
The integrity and function of the endothelium played a key role in the prevention of cardiovascular diseases (CVDs). The maintenance of normal endothelial function not only depended on pre-existing endothelial cells, but also included the recruitment...
2013, 31(1): 14-18.
doi: 10.3969/j.issn.1006-0111.2013.01.004
Abstract:
With the development of the living standard, the incidence of gout was rising and the trend of patient age with gout getting younger. Developing high-effective and low-adverse anti-gout drugs was a priority of the research agenda. At present, convent...
With the development of the living standard, the incidence of gout was rising and the trend of patient age with gout getting younger. Developing high-effective and low-adverse anti-gout drugs was a priority of the research agenda. At present, convent...
2013, 31(1): 19-21.
doi: 10.3969/j.issn.1006-0111.2013.01.005
Abstract:
Statins were a mainstay in the treatment of hyperlipidemia and used in the primary and secondary prevention of coronary artery disease. Recent studies indicated that there were some cholesterol-independent or pleiotropic effects of statins, including...
Statins were a mainstay in the treatment of hyperlipidemia and used in the primary and secondary prevention of coronary artery disease. Recent studies indicated that there were some cholesterol-independent or pleiotropic effects of statins, including...
2013, 31(1): 22-23,66.
doi: 10.3969/j.issn.1006-0111.2013.01.006
Abstract:
Drug-induced hepato-toxicity was an important reason for the liver disease in elderly,which was four times more common than in adults and might include all known liver disorders. Reports related to drug side effects were rare in people >60 years of a...
Drug-induced hepato-toxicity was an important reason for the liver disease in elderly,which was four times more common than in adults and might include all known liver disorders. Reports related to drug side effects were rare in people >60 years of a...
2013, 31(1): 24-26,60.
doi: 10.3969/j.issn.1006-0111.2013.01.007
Abstract:
Objective To analyze the fragments of 10-hydroxy-7-methyl- homocamptothecin (TOP-01) by electrospray ion trap mass spectrometry and deduce the MS/MS fragment pathway of it. Methods Samples were directly injected into the instrument and the fragmen...
Objective To analyze the fragments of 10-hydroxy-7-methyl- homocamptothecin (TOP-01) by electrospray ion trap mass spectrometry and deduce the MS/MS fragment pathway of it. Methods Samples were directly injected into the instrument and the fragmen...
2013, 31(1): 27-31.
doi: 10.3969/j.issn.1006-0111.2013.01.008
Abstract:
Objective To design the novel triazole derivatives and test their in vitro antifungal activities on the basis of the molecular design model for rational optimization of azole drugs. Methods Ring-open reaction of the oxiranes was used to synthesize ...
Objective To design the novel triazole derivatives and test their in vitro antifungal activities on the basis of the molecular design model for rational optimization of azole drugs. Methods Ring-open reaction of the oxiranes was used to synthesize ...
2013, 31(1): 32-34.
doi: 10.3969/j.issn.1006-0111.2013.01.009
Abstract:
Objective To establish a optimum clarification process of Bairui oral liquid with new ZTCI+1-Ⅱ natural clarifying agents. Methods The effects on clarification of Bairui oral liquid were evaluated based on the factors such as adding sequence, added...
Objective To establish a optimum clarification process of Bairui oral liquid with new ZTCI+1-Ⅱ natural clarifying agents. Methods The effects on clarification of Bairui oral liquid were evaluated based on the factors such as adding sequence, added...
2013, 31(1): 35-37.
doi: 10.3969/j.issn.1006-0111.2013.01.010
Abstract:
Objective To establishing the best extraction technology of polysaccharide in Bletilla striata and researching its physical and chemical properties. Methods Water extraction and buck formulation, cellulose enzyme hydrolysis and ultrasonic extracti...
Objective To establishing the best extraction technology of polysaccharide in Bletilla striata and researching its physical and chemical properties. Methods Water extraction and buck formulation, cellulose enzyme hydrolysis and ultrasonic extracti...
2013, 31(1): 38-41.
doi: 10.3969/j.issn.1006-0111.2013.01.011
Abstract:
Objective To investigate the proliferation inhibition of total alkaloids from Pinellia ternate (TATP) in human lung cancer line A549. Methods The proliferation inhibition of human lung cancer cell line A549 treated with TATP was measured with meth...
Objective To investigate the proliferation inhibition of total alkaloids from Pinellia ternate (TATP) in human lung cancer line A549. Methods The proliferation inhibition of human lung cancer cell line A549 treated with TATP was measured with meth...
2013, 31(1): 42-44.
doi: 10.3969/j.issn.1006-0111.2013.01.012
Abstract:
Objective To study the protective effect and possible mechanism of total flavonoids in Herba Siegesbeckiae on focal cerebral ischemia in rats. Methods Sprague Dawley (SD) rats were randomly divided into 6 groups: sham operation group, model group, ...
Objective To study the protective effect and possible mechanism of total flavonoids in Herba Siegesbeckiae on focal cerebral ischemia in rats. Methods Sprague Dawley (SD) rats were randomly divided into 6 groups: sham operation group, model group, ...
2013, 31(1): 45-48.
doi: 10.3969/j.issn.1006-0111.2013.01.013
Abstract:
Objective To analyze the serum bile acid changes in patient of oral administration of UDCA after hepatocellular carcinoma resection and provide reasonable recommendations for clinical staffs. Methods 89 cases with hepatocellular carcinoma after ta...
Objective To analyze the serum bile acid changes in patient of oral administration of UDCA after hepatocellular carcinoma resection and provide reasonable recommendations for clinical staffs. Methods 89 cases with hepatocellular carcinoma after ta...
2013, 31(1): 49-50,56.
doi: 10.3969/j.issn.1006-0111.2013.01.014
Abstract:
To explore the effect of combined therapy with piperazine ferulate and benazepdl on urinary albumin excretion rate (UAER) in patients with early diabetic nephropathy (DN). Methods A total of 164 children were included in the study, 82 of whom accep...
To explore the effect of combined therapy with piperazine ferulate and benazepdl on urinary albumin excretion rate (UAER) in patients with early diabetic nephropathy (DN). Methods A total of 164 children were included in the study, 82 of whom accep...
2013, 31(1): 51-52,63.
doi: 10.3969/j.issn.1006-0111.2013.01.015
Abstract:
Objective To observe the clinical efficacy and safety of Jiangzhi tablet in the treatment of hyperlipoidemia. Methods 117 patients of hyperlipoidemia were randomly divided into 3 groups. Treatment group (39 patients) were treated with Jiangzhi tab...
Objective To observe the clinical efficacy and safety of Jiangzhi tablet in the treatment of hyperlipoidemia. Methods 117 patients of hyperlipoidemia were randomly divided into 3 groups. Treatment group (39 patients) were treated with Jiangzhi tab...
2013, 31(1): 53-56.
doi: 10.3969/j.issn.1006-0111.2013.01.016
Abstract:
Objective To study the solubility and stability of curcumin in PEG-400 and screen the best suitable stabilizer to improve the autoclave stability. Methods Solubility determination was used to determine the solubility of curcumin in PEG-400.The sta...
Objective To study the solubility and stability of curcumin in PEG-400 and screen the best suitable stabilizer to improve the autoclave stability. Methods Solubility determination was used to determine the solubility of curcumin in PEG-400.The sta...
2013, 31(1): 57-60.
doi: 10.3969/j.issn.1006-0111.2013.01.017
Abstract:
Objective To establish a quality standard for Xiangping chaqing paiqian granules. Methods Chemical methods were used to identify vitamin C in the granules. TLC methods were used to identify green tea extracts and chrysanthemum extracts. Chlorogenic...
Objective To establish a quality standard for Xiangping chaqing paiqian granules. Methods Chemical methods were used to identify vitamin C in the granules. TLC methods were used to identify green tea extracts and chrysanthemum extracts. Chlorogenic...
2013, 31(1): 61-63.
doi: 10.3969/j.issn.1006-0111.2013.01.018
Abstract:
Objective To establish a method for determining Esomeprazole in dog plasma by LC-MS-MS. Methods Diazepam was used as the internal standard,the samples were precipitated with acetonitril. Analytical column was Shim-pack XR-ODS (2 mm×100 mm, 5 μm). T...
Objective To establish a method for determining Esomeprazole in dog plasma by LC-MS-MS. Methods Diazepam was used as the internal standard,the samples were precipitated with acetonitril. Analytical column was Shim-pack XR-ODS (2 mm×100 mm, 5 μm). T...
2013, 31(1): 64-66.
doi: 10.3969/j.issn.1006-0111.2013.01.019
Abstract:
Objective To establish an HPLC method for determination of doxapram hydrochloride glucose injection. Methods COSMOSIL C18 (150 mm×4.6 mm,5 μm) column was adopted. The mobile phase consisted of 0.82 μg/L CH3COONa (using Glacial acetic acid adjust to...
Objective To establish an HPLC method for determination of doxapram hydrochloride glucose injection. Methods COSMOSIL C18 (150 mm×4.6 mm,5 μm) column was adopted. The mobile phase consisted of 0.82 μg/L CH3COONa (using Glacial acetic acid adjust to...
2013, 31(1): 67-68,77.
doi: 10.3969/j.issn.1006-0111.2013.01.020
Abstract:
Objective To analyze the outpatient drug return in 2011 and promote rational drug use. Methods 1 905 prescriptions of drug return in our hospital between January and December in 2011 were collected. Based on The medical organization drug managemen...
Objective To analyze the outpatient drug return in 2011 and promote rational drug use. Methods 1 905 prescriptions of drug return in our hospital between January and December in 2011 were collected. Based on The medical organization drug managemen...
2013, 31(1): 69-71.
doi: 10.3969/j.issn.1006-0111.2013.01.021
Abstract:
Objective To provide references for the troubleshooting of automatic oral drug dispensing system in hospital pharmacy. Methods The specific reasons of the fault when using automatic oral drug dispensing system were analyzed, and the processing meth...
Objective To provide references for the troubleshooting of automatic oral drug dispensing system in hospital pharmacy. Methods The specific reasons of the fault when using automatic oral drug dispensing system were analyzed, and the processing meth...
2013, 31(1): 72-74.
doi: 10.3969/j.issn.1006-0111.2013.01.022
Abstract:
Objective To understand the use of antiepileptic drugs for children with epilepsy in our hospital and provide reference for clinical medication individualization. Methods The varieties of antiepileptic drugs, the blood drug levels and the situatio...
Objective To understand the use of antiepileptic drugs for children with epilepsy in our hospital and provide reference for clinical medication individualization. Methods The varieties of antiepileptic drugs, the blood drug levels and the situatio...
2013, 31(1): 75-77.
doi: 10.3969/j.issn.1006-0111.2013.01.023
Abstract:
In the adverse drug reactions, who should be the one to be responsible for patient suffers, which had been controversial for long time. In the judicial practice, law court often judged hospital to take the responsibility based on the fairness doctrin...
In the adverse drug reactions, who should be the one to be responsible for patient suffers, which had been controversial for long time. In the judicial practice, law court often judged hospital to take the responsibility based on the fairness doctrin...