Comparison of two different methods for preparation inclusion compound of β-cyclodextrin with Peppermint Oil
doi: 10.3969/j.issn.1006-0111.2013.02.013
- Received Date: 2012-05-10
- Rev Recd Date: 2012-07-27
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Key words:
- inclusion compound of β-cyclodextrin with peppermint oil /
- saturated water solution /
- ultrasonic
Abstract: Objective To compare the methods of saturated water solution and ultrasonic for preparation inclusion compound of β-cyclodextrin with peppermint oil. Methods After extraction of peppermint oil, the inclusion compound of β-cyclodextrin with peppermint oil was prepared by saturated water solution method and ultrasonic method. Results The better inclusion method was saturated water solution with higher inclusion rate and yield of inclusion compound. And the optimum inclusion conditions were as follows:peppermint oil(ml):β-cyclodextrin(g)=1:5, stirring for 1 hour, 45℃, β-cyclodextrin(g):water(ml)=1:10. Conclusion The better inclusion method was saturated water solution which was reasonable and convenient.
Citation: | DENG Jing-jing, XU Juan, WU Ye, CHEN Jun-shi, YANG Feng. Comparison of two different methods for preparation inclusion compound of β-cyclodextrin with Peppermint Oil[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(2): 129-130,147. doi: 10.3969/j.issn.1006-0111.2013.02.013 |