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Volume 31 Issue 4
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2013  >  31(4): 307-309

FAN Rong, DANG Da-sheng, ZHAO Qing-chun, SHI Guo-bing. Practice of clinical pharmacists participating in treatment of visual impairment caused by voriconazole in a patient of multiple myeloma[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(4): 307-309. doi: 10.3969/j.issn.1006-0111.2013.04.020
Citation: FAN Rong, DANG Da-sheng, ZHAO Qing-chun, SHI Guo-bing. Practice of clinical pharmacists participating in treatment of visual impairment caused by voriconazole in a patient of multiple myeloma[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(4): 307-309. doi: 10.3969/j.issn.1006-0111.2013.04.020
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Practice of clinical pharmacists participating in treatment of visual impairment caused by voriconazole in a patient of multiple myeloma

doi: 10.3969/j.issn.1006-0111.2013.04.020

  • Department of Pharmacy, General Hospital of Shenyang Military Region, Shenyang 110840, China

  • Received Date: 2012-08-15
  • Rev Recd Date: 2012-09-19
  • Objective To discuss the service mode, contents of pharmaceutical care and the basic knowledge and skills that a clinical pharmacist should master by participating in treatment of visual impairment caused by voriconazole in a patient of multiple myeloma. Methods The case history, past medication and ongoing administration of the patient of multiple myeloma were systematically analyzed to find out the relationship between the adverse reaction and the combined medication. Then rational advice was given according to the pharmacological characteristics and drug concentration of voriconazole. Results The physician accepted the advice and reduced the dose of omeprazole for less suppression of hepatic drug metabolizing enzyme and fewer disturbances on dose of voriconazole. Ten days later visual impairment of the patient was improved. Conclusion Clinical pharmacists should be good at flexibly using pharmacological knowledge, evaluating the effects and risks of medication and planning for pharmaceutical care to reduce or avoid subsequent drug impairment.
  • [1] 陈新谦,金有豫,汤 光. 新编药物学,第17版[M].北京:人民卫生出版社,2011:118.
    [2] 官东秀,冯祚臻,俸小平,等. 伏立康唑药物不良反应文献分析[J]. 齐鲁药事,2009,28(8):507.
    [3] Nolan W, Keith T, Lynn P, et al. Effect of omeprazole on the steady-state pharmacokinetics of voriconazole[J]. Br J Clin Pharmacol,2003,56 Suppl 1:56.
    [4] Maertens J, Theunissen K, Verhoef G,et al. Galactomannan and computed tomography-based preemptive antifungal therapy in neutropenic patients at high risk for invasive fungal infection:a prospective feasibility study[J]. Clin Infect Dis, 2005,41(9):1242.
    [5] 高宁舟,沈 杰,宋钟娟,等. 三唑类抗真菌药物治疗药物监测的研究进展[J]. 药学服务与研究,2009,9(5):336.
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Practice of clinical pharmacists participating in treatment of visual impairment caused by voriconazole in a patient of multiple myeloma

doi: 10.3969/j.issn.1006-0111.2013.04.020
  • Department of Pharmacy, General Hospital of Shenyang Military Region, Shenyang 110840, China
  • Received Date: 2012-08-15
  • Rev Recd Date: 2012-09-19

Abstract: Objective To discuss the service mode, contents of pharmaceutical care and the basic knowledge and skills that a clinical pharmacist should master by participating in treatment of visual impairment caused by voriconazole in a patient of multiple myeloma. Methods The case history, past medication and ongoing administration of the patient of multiple myeloma were systematically analyzed to find out the relationship between the adverse reaction and the combined medication. Then rational advice was given according to the pharmacological characteristics and drug concentration of voriconazole. Results The physician accepted the advice and reduced the dose of omeprazole for less suppression of hepatic drug metabolizing enzyme and fewer disturbances on dose of voriconazole. Ten days later visual impairment of the patient was improved. Conclusion Clinical pharmacists should be good at flexibly using pharmacological knowledge, evaluating the effects and risks of medication and planning for pharmaceutical care to reduce or avoid subsequent drug impairment.

FAN Rong, DANG Da-sheng, ZHAO Qing-chun, SHI Guo-bing. Practice of clinical pharmacists participating in treatment of visual impairment caused by voriconazole in a patient of multiple myeloma[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(4): 307-309. doi: 10.3969/j.issn.1006-0111.2013.04.020
Citation: FAN Rong, DANG Da-sheng, ZHAO Qing-chun, SHI Guo-bing. Practice of clinical pharmacists participating in treatment of visual impairment caused by voriconazole in a patient of multiple myeloma[J]. Journal of Pharmaceutical Practice and Service, 2013, 31(4): 307-309. doi: 10.3969/j.issn.1006-0111.2013.04.020
shu

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