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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2016  >  34(6): 560-562

LOU Huiping, CHAI Suping, WANG Min. Clinical effects of continuous sequential therapy of femoston in 121 cases of menopausal syndrome[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(6): 560-562. doi: 10.3969/j.issn.1006-0111.2016.06.019
Citation: LOU Huiping, CHAI Suping, WANG Min. Clinical effects of continuous sequential therapy of femoston in 121 cases of menopausal syndrome[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(6): 560-562. doi: 10.3969/j.issn.1006-0111.2016.06.019
shu

Clinical effects of continuous sequential therapy of femoston in 121 cases of menopausal syndrome

doi: 10.3969/j.issn.1006-0111.2016.06.019

  • Ninghai County Maternal and Child Health Hospital, Ningbo 315600, China

  • Received Date: 2016-08-31
  • Rev Recd Date: 2016-10-14
  • Objective To explore the clinical efficacy and safety of continuous sequential hormone replacement therapy of femoston for menopausal syndrome. Methods 121 cases of menopausal syndrome at expert outpatient service in our hospital from January 2014 to October 2015 received hormone replacement therapy of femoston for 24 weeks. Before and after treatment, Kupperman score, blood follicle stimulating hormone (FSH), estradiol (E2), luteinizing hormone (LH) and endometrial thickness were determined. Results With the prolonging of treatment time, patient's menopausal symptoms gradually relieved. Kupperman scores were declining. After 6 courses of treatment, patient's menopausal symptoms completely eased. Kupperman scores decreased by 95.0% (P<0.01), serum FSH and LH decreased significantly (P < 0.05 and P < 0.01) and serum E2 increased notably (P<0.01) without endometrial thickness changes (P>0.05). Conclusion Continuous sequential therapy of femoston can effectively relieve menopausal syndrome and control the menstrual cycle and the endocrine level without stimulating the endometrium excessively.
  • [1] 丰有吉, 沈铿. 妇产科学[M].2版. 北京:人民卫生出版社, 2010:263.
    [2] 柴光兰, 辛丽娟, 朱金红. 芬吗通治疗围绝经期综合征74例疗效观察[J]. 中国实用医刊, 2014, 41(22):37-38.
    [3] 张雪君. 芬吗通治疗妇女围绝经期综合征的临床疗效观察[J]. 中国计划生育学杂志, 2015, 23(5):330-332.
    [4] 吴惠芹,吴凡. 芬吗通治疗女性更年期综合征的临床研究[J]. 临床与病理杂志, 2015, 35(12):2133-2138.
    [5] 贺瑞芹. 复方制剂芬吗通治疗妇女围绝经期综合征的临床疗效观察[J]. 医疗装备, 2016, 29(4):77-78.
    [6] 王冰,杨勇,王仲奇,等. 芬吗通治疗月经失调180例[J]. 中国药业, 2015, 24(19):120-122.
    [7] 王碧芬,陆海英,郑小平,等. 疏肝解郁汤联用芬吗通治疗更年期综合征120例观察[J]. 浙江中医杂志, 2016, 51(4):251-252.
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Clinical effects of continuous sequential therapy of femoston in 121 cases of menopausal syndrome

doi: 10.3969/j.issn.1006-0111.2016.06.019
  • Ninghai County Maternal and Child Health Hospital, Ningbo 315600, China
  • Received Date: 2016-08-31
  • Rev Recd Date: 2016-10-14

Abstract: Objective To explore the clinical efficacy and safety of continuous sequential hormone replacement therapy of femoston for menopausal syndrome. Methods 121 cases of menopausal syndrome at expert outpatient service in our hospital from January 2014 to October 2015 received hormone replacement therapy of femoston for 24 weeks. Before and after treatment, Kupperman score, blood follicle stimulating hormone (FSH), estradiol (E2), luteinizing hormone (LH) and endometrial thickness were determined. Results With the prolonging of treatment time, patient's menopausal symptoms gradually relieved. Kupperman scores were declining. After 6 courses of treatment, patient's menopausal symptoms completely eased. Kupperman scores decreased by 95.0% (P<0.01), serum FSH and LH decreased significantly (P < 0.05 and P < 0.01) and serum E2 increased notably (P<0.01) without endometrial thickness changes (P>0.05). Conclusion Continuous sequential therapy of femoston can effectively relieve menopausal syndrome and control the menstrual cycle and the endocrine level without stimulating the endometrium excessively.

LOU Huiping, CHAI Suping, WANG Min. Clinical effects of continuous sequential therapy of femoston in 121 cases of menopausal syndrome[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(6): 560-562. doi: 10.3969/j.issn.1006-0111.2016.06.019
Citation: LOU Huiping, CHAI Suping, WANG Min. Clinical effects of continuous sequential therapy of femoston in 121 cases of menopausal syndrome[J]. Journal of Pharmaceutical Practice and Service, 2016, 34(6): 560-562. doi: 10.3969/j.issn.1006-0111.2016.06.019
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