Evaluation on the clinical utilization of human serum albumin in ICU patients

ZHOU Ting; YANG Zhen; LU Saihua; LIU Xiufeng; ZHANG Ye; XU Feng

doi:10.3969/j.issn.1006-0111.2017.02.018

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Objective To evaluate the utilization of human serum albumin (HSA) in intensive care unit (ICU) to promote rational use of HSA clinically. Methods Data were collected from the patients received HSA therapy during the period of January 1, 2015 to December 31, 2015. The indications and usage of HSA were analyzed statistically. Results 416 bottles of HSA were administered to 64 patients. The average dose was 62.5g per patient. The most popular indication was for hypoproteinemia (39.1%) followed by encephaledema, craniocerebral trauma, shock and tumors. Before the HSA therapy, 36 patients (56.3%) had albumin level of 15-25 g/L and 23 patients (35.9%) of 25-35 g/L. Conclusion HSA is widely used in ICU for different indications. Some misuses still exist. Guidelines for proper use of HSA are needed to guarantee its rational use. HSA should be used strictly following these guidelines.

Evaluation on the clinical utilization of human serum albumin in ICU patients

1. Department of Pharmacy, South Campus, Sixth People's Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 201499, China

2. Department of Pharmacy, Fengxian Hospital, Jinzhou Medical University, Shanghai 201499, China

Received Date: 2016-05-13

Rev Recd Date: 2016-06-16

Key words:

Abstract: Objective To evaluate the utilization of human serum albumin (HSA) in intensive care unit (ICU) to promote rational use of HSA clinically. Methods Data were collected from the patients received HSA therapy during the period of January 1, 2015 to December 31, 2015. The indications and usage of HSA were analyzed statistically. Results 416 bottles of HSA were administered to 64 patients. The average dose was 62.5g per patient. The most popular indication was for hypoproteinemia (39.1%) followed by encephaledema, craniocerebral trauma, shock and tumors. Before the HSA therapy, 36 patients (56.3%) had albumin level of 15-25 g/L and 23 patients (35.9%) of 25-35 g/L. Conclusion HSA is widely used in ICU for different indications. Some misuses still exist. Guidelines for proper use of HSA are needed to guarantee its rational use. HSA should be used strictly following these guidelines.

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Evaluation on the clinical utilization of human serum albumin in ICU patients

doi: 10.3969/j.issn.1006-0111.2017.02.018

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