Determination of indometacin in glucosamine indometacin enteric coated tablets by HPLC
- Received Date: 1999-12-06
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Key words:
- indometacin /
- glucosamine indometacin /
- HPLC /
- determination
Abstract: OBJECTIVE To establish a method for the determination the indometacin content in glucosamine indometacin enteric-coated tablets by HPLC.METHODS Using SPHERI-5 RP-18 column,with methanol-water-acetonitrile-phosphoric acid(60:25:15:0.04) as the mobile.RESULTS An excellent linear relationship was obtained between the peak area and the concentration with the range of 10~60μg/ml.The average recoverary was 99.56%,the RSD was 0.65%.CONCLUSION This method is accurate,quick and reproducible.
Citation: | WANG Qiong-fen, MEI Hong-hui. Determination of indometacin in glucosamine indometacin enteric coated tablets by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2000, (2): 91-92,95. |