Determination of aminophylline dexamethasone sodium phosphate, diazepam in gaoyuankang capsules by HPLC
- Received Date: 2001-07-30
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Key words:
- HPLC /
- aminophylline /
- dexamethasone sodium phosphate /
- diazepam
Abstract: To establish a method for determination of three constituents in Gaoyuankang capasules.METHODS A hypersil ODS column with a mobile phase composed of methol-phosphate buffer sulotion(55:45) was used.The detection wavelength was 240nm.RESULTS The linear response range was as follows aminophylline 60~140μg·ml-1(r=0.9995),dexamethasone sodium phosphate 4.8~11.2μg·ml-1(r=0.9993),diazepam 16.8~39.2μg·ml-1(r=0.9998),The recoveries of aminophylline,dexamethasone sodium phosphate,diazepam were 99.3%,99.4%,100.5%.CONCLUSIONS The method is simple,rapid and accurate.
Citation: | LOU Zi-yang, XU Li, WANG Xue-zhao, CHAI Yi-feng. Determination of aminophylline dexamethasone sodium phosphate, diazepam in gaoyuankang capsules by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2001, (6): 352-353. |