Determination of trimethoprim in compound naphthoquine tablets by di-wavelength spectrophotosmetry
- Received Date: 2001-06-13
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Key words:
- di-wavelength spectrophotosmetry /
- naphthoquine phosphate /
- trimethoprim /
- compound preparation
Abstract: OBJECTIVE To develop a method for determination of trimethoprim in compound naphthoquine Tablets.METHODS Detected at 271nm, with referenced wavelength at 361nm. RESULTS Within 6.24~31.20μg/ml, TMP had a good linearity (r=0.9999).The average recovery was 100.9%, with the RSD of 0.24%(n=6).CONCLUSION The method was simple, rapid, accurate, and can be used both as the determination of content and the determination of dissolve.
Citation: | XIAO Wen-zhong, ZHANG Mei-yi, LIN Yan-fang, ZHAN Li-zhi, FU Lin-chun, LI Guo-qiao. Determination of trimethoprim in compound naphthoquine tablets by di-wavelength spectrophotosmetry[J]. Journal of Pharmaceutical Practice and Service, 2001, (6): 354-355,331. |