Effect of adapalene gel in the treatment of acne vulgaris
- Received Date: 2001-09-13
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Key words:
- 0.1% adapalene gel /
- 0.025% tretinoin /
- acne vulgaris
Abstract: OBJECTIVE To observe the effect and safety of 0.1% adapalene gel in the treatment for patients with acne vulgaris.METHODS 160 patients with acne vulgaris topically applied 0.1% adapalene gel (80cases) and 0.025% tretinoin gel (80 cases), respectively. The efficacy was evaluated according to the reductive proportion of inflammatory and non-inflammatory lesions before and after the treatment.RESULTS No significant difference was detected between two treatment groups in the rate of cure, marked improvement and total efficacy rate. The incidence rate of adverse reaction in 0.1%adapalene gel group was much lower than in 0.025% tretinoin gel group. CONCLUSION 0.1% adapalent gel was an effective and safe drug of topical treatment for patients with acne vulgaris.
Citation: | ZHENG Li-bao, HUANG Wei-dong, CHEN Jing, ZHANG Hong, FU Jiang-zhou. Effect of adapalene gel in the treatment of acne vulgaris[J]. Journal of Pharmaceutical Practice and Service, 2002, (1): 10-11,28. |