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WU Hong-wei, ZHANG Jing, CHEN Cai-ming, CAI Lin. The study on the stability of compatibility of zedoary turmeric oil and glucose injection with five drugs respectively[J]. Journal of Pharmaceutical Practice and Service, 2002, (1): 21-24.
Citation: WU Hong-wei, ZHANG Jing, CHEN Cai-ming, CAI Lin. The study on the stability of compatibility of zedoary turmeric oil and glucose injection with five drugs respectively[J]. Journal of Pharmaceutical Practice and Service, 2002, (1): 21-24.

The study on the stability of compatibility of zedoary turmeric oil and glucose injection with five drugs respectively

  • Received Date: 2001-09-06
  • OBJECTIVE To inspect the stability of compatibility of zedoary turmeric oil and glucose injection with cefazolin sodium for injection,cefoperazone sodium for injection,piperacillin sodium for injection and vitamin C plus dexamethason sodium phosphate injection, respectively.METHODS The spectrophotometry was used to measure the ongoing change of the content of zedoary turmeric oil after compatibility.The HPLC was used to measure the ongoing change of content of cefazolin sodium,cefoperazone sodium and piperacillin sodium after compatibility.RESULTS According to the compatibility modeling on clinical concentration,in the case of compatibility of zedoary turmeric oil and glucose injection with cefoperazone,more than 30% of zedoary turmeric oil decomposed,so it is unstable compatibility.The rest three compatibilities are relatively stable.There is no obvious ongoing change in appearnce,pH and content.CONCLUSION The compatibility of zedoary turmeric oil and glucose injection with cefoperazone sodium is unsuitable.The rest four drugs compatibilities are feasible and can be applied in the intravenous drip.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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The study on the stability of compatibility of zedoary turmeric oil and glucose injection with five drugs respectively

Abstract: OBJECTIVE To inspect the stability of compatibility of zedoary turmeric oil and glucose injection with cefazolin sodium for injection,cefoperazone sodium for injection,piperacillin sodium for injection and vitamin C plus dexamethason sodium phosphate injection, respectively.METHODS The spectrophotometry was used to measure the ongoing change of the content of zedoary turmeric oil after compatibility.The HPLC was used to measure the ongoing change of content of cefazolin sodium,cefoperazone sodium and piperacillin sodium after compatibility.RESULTS According to the compatibility modeling on clinical concentration,in the case of compatibility of zedoary turmeric oil and glucose injection with cefoperazone,more than 30% of zedoary turmeric oil decomposed,so it is unstable compatibility.The rest three compatibilities are relatively stable.There is no obvious ongoing change in appearnce,pH and content.CONCLUSION The compatibility of zedoary turmeric oil and glucose injection with cefoperazone sodium is unsuitable.The rest four drugs compatibilities are feasible and can be applied in the intravenous drip.

WU Hong-wei, ZHANG Jing, CHEN Cai-ming, CAI Lin. The study on the stability of compatibility of zedoary turmeric oil and glucose injection with five drugs respectively[J]. Journal of Pharmaceutical Practice and Service, 2002, (1): 21-24.
Citation: WU Hong-wei, ZHANG Jing, CHEN Cai-ming, CAI Lin. The study on the stability of compatibility of zedoary turmeric oil and glucose injection with five drugs respectively[J]. Journal of Pharmaceutical Practice and Service, 2002, (1): 21-24.

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