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Volume 21 Issue 2
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2003  >  (2): 82-83

ZHANG Xu, TONG Zhi-qing, JIANG Tie-fu, CAO Bing-xing. The discussion on the endotoxin inspection method of cerebrolysin injection[J]. Journal of Pharmaceutical Practice and Service, 2003, (2): 82-83.
Citation: ZHANG Xu, TONG Zhi-qing, JIANG Tie-fu, CAO Bing-xing. The discussion on the endotoxin inspection method of cerebrolysin injection[J]. Journal of Pharmaceutical Practice and Service, 2003, (2): 82-83.
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The discussion on the endotoxin inspection method of cerebrolysin injection

  • The 463rd Hospital of PLA, Shenyang 110042, China

  • Received Date: 2002-12-28
  • OBJECTIVE To establish the inspection method of endotoxin in cerebrolysin injection. METHODS The experiment is implemented according to the request of endotoxin inspection method colledted in China Pharmacopeia(Ⅱ, 2000Ed).RESULTS The experiment showed that the interference elements can be excluded by diluting cerebrolysin injection 30 times, and it is effective that endotoxin can be tested by amebocyte lysate with accuracy of 0.5EU·mL-1.CONCLUSION For daily pyrogon test of cerebrolysin injection,enotoxin inspection method can be used instead of domestic rabbit method.
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The discussion on the endotoxin inspection method of cerebrolysin injection

  • The 463rd Hospital of PLA, Shenyang 110042, China
  • Received Date: 2002-12-28

Abstract: OBJECTIVE To establish the inspection method of endotoxin in cerebrolysin injection. METHODS The experiment is implemented according to the request of endotoxin inspection method colledted in China Pharmacopeia(Ⅱ, 2000Ed).RESULTS The experiment showed that the interference elements can be excluded by diluting cerebrolysin injection 30 times, and it is effective that endotoxin can be tested by amebocyte lysate with accuracy of 0.5EU·mL-1.CONCLUSION For daily pyrogon test of cerebrolysin injection,enotoxin inspection method can be used instead of domestic rabbit method.

ZHANG Xu, TONG Zhi-qing, JIANG Tie-fu, CAO Bing-xing. The discussion on the endotoxin inspection method of cerebrolysin injection[J]. Journal of Pharmaceutical Practice and Service, 2003, (2): 82-83.
Citation: ZHANG Xu, TONG Zhi-qing, JIANG Tie-fu, CAO Bing-xing. The discussion on the endotoxin inspection method of cerebrolysin injection[J]. Journal of Pharmaceutical Practice and Service, 2003, (2): 82-83.
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