Assay for bacteririal endotoxin in papaverine hydrochloride and sodium chloride injection
- Received Date: 2003-10-28
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Key words:
- papaverine hydrochloride and sodium chlorid injection /
- bacterial endotoxin /
- Gel-clot method
Abstract: OBJECTIVE To establish the method of assay for the bacterial endotoxin in papaverine hydrochlo-ride and sodium chloride injection. METHODS Inhibition and enhancement test was performed with limulus ameboeytc lysate manufactured by two different companies. RESULTS:The injection will not interfere to the bacterial endotoxins test. CONCLUSIONS The results suggest that bacterial endotoxins test(gel-clot method)can be used as an replaceable method for the rabbit pyrogen test for papaverine hydrochloride and sodium chloride injection.
Citation: | JIN Wei-hong JU Hong-feng, . Assay for bacteririal endotoxin in papaverine hydrochloride and sodium chloride injection[J]. Journal of Pharmaceutical Practice and Service, 2003, (6): 341-343. |