Determination of ephedrine hydrochloride in kegan nasal drops by HPLC

LIU Mei-juan; LOU Ping

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Volume 21 Issue 6

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Article Navigation > Journal of Pharmaceutical Practice and Service > 2003 > (6): 369-370

LIU Mei-juan, LOU Ping. Determination of ephedrine hydrochloride in kegan nasal drops by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2003, (6): 369-370.

Citation:

LIU Mei-juan, LOU Ping. Determination of ephedrine hydrochloride in kegan nasal drops by HPLC[J]. Journal of Pharmaceutical Practice and Service, 2003, (6): 369-370.

Determination of ephedrine hydrochloride in kegan nasal drops by HPLC

LIU Mei-juan¹,
LOU Ping²

1.
Linyi hospitaL for heath protection of woman and child, Linyi 276003, China
2.
Linyi Institute for Drug ControL

Received Date: 2003-10-28

Abstract

OBJECTIVE To develop a method for the determination of ephedrine hydrochloride in kegan nasal drops by HPLC. METHODS The chromatographic condition included ODS column and the mobile phase consisting of 0.01 mol/L KH₂PO₄ solution-acetonitrile(40:60).The detection wavelengthwas at 215nm,flow rate at 1.0mL/min. RESULTS:The calibration curve was linear over the rage of 40-96μg/mL. The average recovery was 96.1%.The method precision(RSD%)was 1.2%(n=5).CONCLUSION The method was convenient and accurate for the quality control of the preparation.
- HPLC,
- ephedrine hydrochloride,
- content
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

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