Thioazolidinediones and insulin resistance
- Received Date: 2003-11-20
-
Key words:
- thiazolidinediones /
- insulin resistance /
- type 2 diabetes mellitus /
- adverse effects
Abstract: Objective To review the mechanisms of action of thiazolidinediones, clinical efficacy in patients with type 2 diabetes mellitus, effects on insulin sensitivity, side-effects and guideline for the clinical use of thiazolidinediones. Methods Analyze the correlated literature at home and abroad. Results Thiazolidinediones improve insulin sensitivity of patients with insulin resistance and type 2 diabetes mellitus through several mechanisms. Conclusion Thiazolidinediones are very valuable in clinic, but patient should pay attention to their adverse effects.
Citation: | BAI Hong-yan, ZHOU Wen-jun, ZHANG Yan. Thioazolidinediones and insulin resistance[J]. Journal of Pharmaceutical Practice and Service, 2004, (2): 65-67. |