Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code

YANG Sheng-hong, LI Zhi-yuan, WANG qiang, HUANG Mao. Study on the choice of stimulation to motion sickness in rats[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 78-79,87.
Citation: YANG Sheng-hong, LI Zhi-yuan, WANG qiang, HUANG Mao. Study on the choice of stimulation to motion sickness in rats[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 78-79,87.

Study on the choice of stimulation to motion sickness in rats

  • Received Date: 2006-12-25
  • Objective: To compare the effect of four stimulator to induce motion sickness in rats. Methods: 40 male SD rats were di-vided into four groups randomly.The induced motion sickness was determined by the assay of kaolin intake 2 days before and 2 days after rotational stimulation.GroupⅠwere stimulated in a rotator with ahernately variable speed for 1h,which were rotated clockwise around a horizontal axis at an angular acceleration of 18°/s2 until the angular velocity reached 120°/s.Then the device was decelerated at an angu-lar acceleration of 48°/s2 until rotation stopped.GroupⅡwere treated identically except that they were rotated for 1.5h.GroupⅢwere stimulated with alternately variable speed for 1h,which rotated clockwise around a horizontal axis at an angular acceleration of 48°/s2 un-til the angular velocity reached 120°/s.Then the device was decelerated at the same rate until rotation stopped.GroupⅣwere rotated at 120°/s clockwise around a horizontal axis. Results: Among the four groups,the difference of kaolin intake before and after rotation of groupⅠ,groupⅡand groupⅢwere significantly more than that of control group(groupⅡP<0.01,groupⅠand groupⅢP<0.05).The difference of kaolin intake before and after rotation of groupⅡwas more than others(P<0.01). Conclusion: The rotational stimulation of groupⅠ,groupⅡand groupⅢcan induce motion sickness in rats,and groupⅡwere the most effective.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Article Metrics

Article views(2473) PDF downloads(325) Cited by()

Related
Proportional views

Study on the choice of stimulation to motion sickness in rats

Abstract: Objective: To compare the effect of four stimulator to induce motion sickness in rats. Methods: 40 male SD rats were di-vided into four groups randomly.The induced motion sickness was determined by the assay of kaolin intake 2 days before and 2 days after rotational stimulation.GroupⅠwere stimulated in a rotator with ahernately variable speed for 1h,which were rotated clockwise around a horizontal axis at an angular acceleration of 18°/s2 until the angular velocity reached 120°/s.Then the device was decelerated at an angu-lar acceleration of 48°/s2 until rotation stopped.GroupⅡwere treated identically except that they were rotated for 1.5h.GroupⅢwere stimulated with alternately variable speed for 1h,which rotated clockwise around a horizontal axis at an angular acceleration of 48°/s2 un-til the angular velocity reached 120°/s.Then the device was decelerated at the same rate until rotation stopped.GroupⅣwere rotated at 120°/s clockwise around a horizontal axis. Results: Among the four groups,the difference of kaolin intake before and after rotation of groupⅠ,groupⅡand groupⅢwere significantly more than that of control group(groupⅡP<0.01,groupⅠand groupⅢP<0.05).The difference of kaolin intake before and after rotation of groupⅡwas more than others(P<0.01). Conclusion: The rotational stimulation of groupⅠ,groupⅡand groupⅢcan induce motion sickness in rats,and groupⅡwere the most effective.

YANG Sheng-hong, LI Zhi-yuan, WANG qiang, HUANG Mao. Study on the choice of stimulation to motion sickness in rats[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 78-79,87.
Citation: YANG Sheng-hong, LI Zhi-yuan, WANG qiang, HUANG Mao. Study on the choice of stimulation to motion sickness in rats[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 78-79,87.

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return