Message Board

Respected readers, authors and reviewers, you can add comments to this page on any questions about the contribution, review,        editing and publication of this journal. We will give you an answer as soon as possible. Thank you for your support!

Name
E-mail
Phone
Title
Content
Verification Code

ZHAO Nan, TANG Zhen, WANG Yan-ping, XUE Wan-li. Preparation and study of pharmaceutics of 5-ISMN orally disintegrating tablets[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 94-97.
Citation: ZHAO Nan, TANG Zhen, WANG Yan-ping, XUE Wan-li. Preparation and study of pharmaceutics of 5-ISMN orally disintegrating tablets[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 94-97.

Preparation and study of pharmaceutics of 5-ISMN orally disintegrating tablets

  • Received Date: 2006-11-22
  • Objective: To optimize the formulation of 5-ISMN orally disintegrating tablets,and inspect quality of prepared tablets. Methods: The orthogonal design was used and HPLC was used to determine the concentration. Results: Besides 5-ISMN,the tablets were composed of croscarmellose sodium 3%,mannite 15%,lactose 31%,MCC/L-HPC ratio was 8:2(32%,8%).The prepared tablets disintegrated completely in 20s,dissolved more than 80% in 2min and tasty fine. Conclusion: Choose properly excipients,we can produce orally rapidly-disintegrating tablets of rapidly disintegrating,tasty well and rapid absorption.
  • 加载中
通讯作者: 陈斌, bchen63@163.com
  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

  1. 本站搜索
  2. 百度学术搜索
  3. 万方数据库搜索
  4. CNKI搜索

Article Metrics

Article views(2503) PDF downloads(228) Cited by()

Related
Proportional views

Preparation and study of pharmaceutics of 5-ISMN orally disintegrating tablets

Abstract: Objective: To optimize the formulation of 5-ISMN orally disintegrating tablets,and inspect quality of prepared tablets. Methods: The orthogonal design was used and HPLC was used to determine the concentration. Results: Besides 5-ISMN,the tablets were composed of croscarmellose sodium 3%,mannite 15%,lactose 31%,MCC/L-HPC ratio was 8:2(32%,8%).The prepared tablets disintegrated completely in 20s,dissolved more than 80% in 2min and tasty fine. Conclusion: Choose properly excipients,we can produce orally rapidly-disintegrating tablets of rapidly disintegrating,tasty well and rapid absorption.

ZHAO Nan, TANG Zhen, WANG Yan-ping, XUE Wan-li. Preparation and study of pharmaceutics of 5-ISMN orally disintegrating tablets[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 94-97.
Citation: ZHAO Nan, TANG Zhen, WANG Yan-ping, XUE Wan-li. Preparation and study of pharmaceutics of 5-ISMN orally disintegrating tablets[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 94-97.

Catalog

    /

    DownLoad:  Full-Size Img  PowerPoint
    Return
    Return