Comparison of antitumor effect of complex shark cartilage and its components in mice transplanted with sarcoma 180
- Received Date: 2007-01-08
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Key words:
- complex shark cartilage /
- shark cartilage /
- cyclophosphamide /
- sarcoma 180
Abstract: Objective: To compare the antitumor effect of complex shark cartilage with its components alone. Methods: Complex shark cartilage and its components,Chinese tranditional medicines and shark cartilage,were given ig in sarcoma S180-bearing mice,re-spectively. Results: Complex shark cartilage at dose 5.0,2.5,and 1.25g/(kg·d)had significant antitumor effects.The inhibition rates against the tumors were 80.2%~65.6%.The Chinese tranditional medicines(2.4,1.2,and 0.6g/kg)and the shark cartilage (2.6,1.3,and 0.65g/kg)at the doses which were equal to those in the complex shark cartilage had mild antitumor effects.The inhibi-tion rates against the tumor were below 30%. Conclusion: The components of complex shark cartilage have significant antitumor effect in S180-bearing mice.
Citation: | SU Kai-zhong, MA Hong-mei, WEI Wen-shu. Comparison of antitumor effect of complex shark cartilage and its components in mice transplanted with sarcoma 180[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 80-81. |