Improvement on mobile phase of dissolution and determination of terfenadine tablets

WU Hai-wen

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Volume 25 Issue 2

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Article Navigation > Journal of Pharmaceutical Practice and Service > 2007 > (2): 98-99

WU Hai-wen. Improvement on mobile phase of dissolution and determination of terfenadine tablets[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 98-99.

Citation:

WU Hai-wen. Improvement on mobile phase of dissolution and determination of terfenadine tablets[J]. Journal of Pharmaceutical Practice and Service, 2007, (2): 98-99.

Improvement on mobile phase of dissolution and determination of terfenadine tablets

WU Hai-wen

Ningbo Institute for Drug Control,Ningbo 315040,China

Received Date: 2006-01-16

Abstract

Objective: To find a ideal and unified mobile phase both of dissolution test and content determination of terfenadine tablets. Methods: HPLC was used. Results: The mobile phaseⅢ[a mobile phase composed of acetonitrile-phosphate buffer(50:50)] was applied,t_R is shorter,the peak shape is better and the methods are specific and sensitive. Conclusion: The mobile phaseⅢis recommended as a ideal and unified mobile phase of dissolution and determination for terfenadine tablets.
- terfenadine tablets,
- HPLC method,
- dissolution,
- determination of content
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

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