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Volume 25 Issue 6
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Article Navigation >  Journal of Pharmaceutical Practice and Service  > 2007  >  (6): 382-385

ZHANG Lan, YANG Shui-xin. Analysis of the lignans components in decoction granule of Schisandra chinensis[J]. Journal of Pharmaceutical Practice and Service, 2007, (6): 382-385.
Citation: ZHANG Lan, YANG Shui-xin. Analysis of the lignans components in decoction granule of Schisandra chinensis[J]. Journal of Pharmaceutical Practice and Service, 2007, (6): 382-385.
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Analysis of the lignans components in decoction granule of Schisandra chinensis

  • 1.

    Changxing People's Hospital of Zhejiang Province,Changxing 313100 China;Central Hospital of Huzhou of Zhejiang Province,Huzhou 313000,China

  • 2.

    Changxing People's Hospital of Zhejiang Province,Changxing 313100 China;Central Hospital of Huzhou of Zhejiang Province,Huzhou 313000,China

  • Received Date: 2006-12-26
  • Objective :To establish a method to determine the active components of lignans(schisandrin,schisandtherin A,deoxyschizandrin and schisandrin B) in decoction granule of Schisandra chinensis.To find and anylyse the difference of components of different factories. Methods :RP-HPLC method was used.The column was Hypersil ODS C18(4.6 mm×250 mm,10 μm) with the mobile phase of acetonititrile(A) and H2O(B),the flow rate was 1.0 mL/min,the column temperature was set at 25 ℃ and the detection wavelength was set at 254 nm. Results : The content of schisandrin was from 0 to 1.292 3mg/package,schisandtherin A was from 0 to 0.560 8 mg/package,deoxyschizandrin was from 0 to 0.168 8mg/package.Schisandrin B was not detected. Conclusion : The content of schisandrin,schisandtherin A and deoxyschizandrin were obviously different in decoction granule of Schisandra chinensis produced by different factories.
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  • 1. 

    沈阳化工大学材料科学与工程学院 沈阳 110142

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Analysis of the lignans components in decoction granule of Schisandra chinensis

  • 1. Changxing People's Hospital of Zhejiang Province,Changxing 313100 China;Central Hospital of Huzhou of Zhejiang Province,Huzhou 313000,China
  • 2. Changxing People's Hospital of Zhejiang Province,Changxing 313100 China;Central Hospital of Huzhou of Zhejiang Province,Huzhou 313000,China
  • Received Date: 2006-12-26

Abstract: Objective :To establish a method to determine the active components of lignans(schisandrin,schisandtherin A,deoxyschizandrin and schisandrin B) in decoction granule of Schisandra chinensis.To find and anylyse the difference of components of different factories. Methods :RP-HPLC method was used.The column was Hypersil ODS C18(4.6 mm×250 mm,10 μm) with the mobile phase of acetonititrile(A) and H2O(B),the flow rate was 1.0 mL/min,the column temperature was set at 25 ℃ and the detection wavelength was set at 254 nm. Results : The content of schisandrin was from 0 to 1.292 3mg/package,schisandtherin A was from 0 to 0.560 8 mg/package,deoxyschizandrin was from 0 to 0.168 8mg/package.Schisandrin B was not detected. Conclusion : The content of schisandrin,schisandtherin A and deoxyschizandrin were obviously different in decoction granule of Schisandra chinensis produced by different factories.

ZHANG Lan, YANG Shui-xin. Analysis of the lignans components in decoction granule of Schisandra chinensis[J]. Journal of Pharmaceutical Practice and Service, 2007, (6): 382-385.
Citation: ZHANG Lan, YANG Shui-xin. Analysis of the lignans components in decoction granule of Schisandra chinensis[J]. Journal of Pharmaceutical Practice and Service, 2007, (6): 382-385.
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