Effects of ondansetron,granisetron,and tropisetron on vomiting caused by transcatheter arterial chemoembolization (TACE)
- Received Date: 2007-04-16
- Rev Recd Date: 2006-10-30
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Key words:
- ondansetron /
- granisetron /
- tropisetron /
- liver neoplasms /
- transarterial chemoembolization(TACE) /
- vomit /
- prevent
Abstract: Objective: To compare the prophylactic efficacy of ondansetron,granisetron,and tropisetron on vomiting caused by TACE. Methods: 120 patients(with primary hepatocellular carcinoma) were randomly divided into four groups to receive ondanstron,granisetron,tropisetron via liver artery injection (n=30) and combined with metoclopramide as controls (n=30).The antiemetic efficacies were compared among the four groups for 5 consecutive days after TACE. Results: The effective rate of tropisetron group was significantly higher than that of the control group (P<0.05). Conclusion: Tropisetron is an effective antiemetic drug in controlling vomiting caused by TACE and should be advocated in clinical practice.
Citation: | LIU Qiu-ru, MA Ai-ying, SHEN Jie. Effects of ondansetron,granisetron,and tropisetron on vomiting caused by transcatheter arterial chemoembolization (TACE)[J]. Journal of Pharmaceutical Practice and Service, 2008, (1): 43-45. |