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WANG Jin-rui, CHEN Jian-ming, Zhang Yue. Studies on the self-emulsifying drug delivery systems of adefovir dipivoxil[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(2): 118-121.
Citation: WANG Jin-rui, CHEN Jian-ming, Zhang Yue. Studies on the self-emulsifying drug delivery systems of adefovir dipivoxil[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(2): 118-121.

Studies on the self-emulsifying drug delivery systems of adefovir dipivoxil

  • Received Date: 2008-09-22
  • Objective : To search for the optimum formula ratio for the self-emulsifying drug delivery systems of adefovir dipivoxil. Methods : The recipe of the self-emulsifying drug delivery systems of adefovir dipivoxil formation was optimized by studying the pseudo-ternary phase diagram,the self-emulsifying rate,particle size.Adefovir was successfully embedded in the SEDDS emulsion. Results :The optimized prescription was tricaprylin as oil,Cremophor EL35 as surfactant,with the oil and the surfactant ratio was 73. Conclusions :The preliminary adefovir dipivoxil Self-emulsifying prepartion has been prepared.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Studies on the self-emulsifying drug delivery systems of adefovir dipivoxil

Abstract: Objective : To search for the optimum formula ratio for the self-emulsifying drug delivery systems of adefovir dipivoxil. Methods : The recipe of the self-emulsifying drug delivery systems of adefovir dipivoxil formation was optimized by studying the pseudo-ternary phase diagram,the self-emulsifying rate,particle size.Adefovir was successfully embedded in the SEDDS emulsion. Results :The optimized prescription was tricaprylin as oil,Cremophor EL35 as surfactant,with the oil and the surfactant ratio was 73. Conclusions :The preliminary adefovir dipivoxil Self-emulsifying prepartion has been prepared.

WANG Jin-rui, CHEN Jian-ming, Zhang Yue. Studies on the self-emulsifying drug delivery systems of adefovir dipivoxil[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(2): 118-121.
Citation: WANG Jin-rui, CHEN Jian-ming, Zhang Yue. Studies on the self-emulsifying drug delivery systems of adefovir dipivoxil[J]. Journal of Pharmaceutical Practice and Service, 2009, 27(2): 118-121.

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