Compatible stability of glucose and sodium potassium chloride injection mixing with cefepime Hydrochloride for injection

WEI Jing-hai; WEI Jing-hai; WEI Jing-hai; WEI Jing-hai

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Volume 28 Issue 3

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Article Navigation > Journal of Pharmaceutical Practice and Service > 2010 > 28(3): 213-214

WEI Jing-hai, WEI Jing-hai, WEI Jing-hai, WEI Jing-hai. Compatible stability of glucose and sodium potassium chloride injection mixing with cefepime Hydrochloride for injection[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 213-214.

Citation:

WEI Jing-hai, WEI Jing-hai, WEI Jing-hai, WEI Jing-hai. Compatible stability of glucose and sodium potassium chloride injection mixing with cefepime Hydrochloride for injection[J]. Journal of Pharmaceutical Practice and Service, 2010, 28(3): 213-214.

Compatible stability of glucose and sodium potassium chloride injection mixing with cefepime Hydrochloride for injection

1.
Department of Pharmacy,Beijing Children's Hospital,Affiliated to Capital University of Medical Sciences,Beijing 100045,China
2.
Department of Pharmaceutical Analysis,Shenyang Pharmaceutical University,Shenyang 110016,China

Received Date: 2009-08-24
Rev Recd Date: 2009-11-03

Abstract

Objective To study the stability of glucose and sodium potassium chloride injection(GNK) mixing with cefepime hydrochloride in room temperature. Methods RP-HPLC was applied to determine the content change of cefepime hydrochloride in different time.The pH,quantity of non-soluble particulate and appearance of mixtures were also observed. Results In room temperature the mixtures produced neither gas nor sediment.The pH,quantity of non-soluble particulate and content did not change within 8 hours. Conclusion The mixtures of GNK mixing with cefepime hydrochloride are stable in 8 hours.
- compatible stability,
- GNK,
- cefepime hydrochloride
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

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