110种藏药抗肿瘤体外筛选实验研究
Antitumor Screening Research from 110 Tibetan Medicines
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摘要: 目的 对110种植物藏药进行抗肿瘤筛选。方法 干燥植物样品粉碎后分别以石油醚及90%乙醇提取。用90%乙醇提取物对体外培养的5种人体肿瘤细胞:乳腺癌、肺癌、直肠癌、口腔上皮癌(耐药性及非耐药性两种)、前列腺癌及一种大鼠神经胶质肿瘤细胞进行筛选实验。结果 有五种藏药:桃儿七果实、藏木香、裸茎金腰、祁连圆柏、苍耳草具有较好的抗肿瘤作用。结论 本研究对进一步研究、开发藏药提供科学的理论依据。Abstract: OBJECTIVE To screen antitumour medicine from 110 Tibetan medicines.METHODS Dried plant materials were ground and were extracted by petrol ether and 90% ethanol separately.The 90% ethernal extracts were used to test cultured five human tumour cells: BC1, Lu1, Co12, KB and LNCaP and one rat tumour cell ASK. RESULTS Five Tibetan medicines were found to display cytotoxic effects in cultured tumor cells. CONCLUSION The result would be used as reference for further Tibetan medicine research.
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Key words:
- antitumor screening /
- tibetan medicines
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