1995 Vol. 13, No. 6
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1995, (6): 327-329.
Abstract:
1995, (6): 332-334.
Abstract:
This article summarized the researches in vitro and in vivo, clinical application of erythromycin as a gastrointestinal prokinetic agent in recent years.
This article summarized the researches in vitro and in vivo, clinical application of erythromycin as a gastrointestinal prokinetic agent in recent years.
1995, (6): 341-348.
Abstract:
Chemical consitituents including triterpenoid saponins, organic acids, esters and polyacetylenes of genus Aralia along with their pharmacological activities are reviewed.
Chemical consitituents including triterpenoid saponins, organic acids, esters and polyacetylenes of genus Aralia along with their pharmacological activities are reviewed.
1995, (6): 350-351.
Abstract:
Compatible stability of compound injection of aminopyrine and micronomicin injection was observed.The results shows that intramuscular injection of the mixed solution is fesible in 1 hour.
Compatible stability of compound injection of aminopyrine and micronomicin injection was observed.The results shows that intramuscular injection of the mixed solution is fesible in 1 hour.
1995, (6): 353-354.
Abstract:
The stability of pefloxacin in routine transfusion solutions were studied. The result showed that pefloxacin is stable when combined with 5% glucose injection,0.9%sodium chloride injection,glucose and sodium chloride injection,compound sodium chloride injection under room temperature, their pH and content changed a little within 24 hours, The result showed that pefloxacin could be added to routine transfusion solutions to unite intravenous drop.
The stability of pefloxacin in routine transfusion solutions were studied. The result showed that pefloxacin is stable when combined with 5% glucose injection,0.9%sodium chloride injection,glucose and sodium chloride injection,compound sodium chloride injection under room temperature, their pH and content changed a little within 24 hours, The result showed that pefloxacin could be added to routine transfusion solutions to unite intravenous drop.
1995, (6): 355-358.
Abstract:
A balanced, randomized and crossover study was conducted in six rabbits. Each rabbit was given diltiazem/propafenone alone or in combination. Pharmacokinetic parameters of propafenone were significantly changed when coadministration with diltiazem. Its Ke and cls/F were both Cmax and AUC0-∞ were increased. On the other hand, some pharmacokinetic parameters of diltiazem were also changed after combination treatment. Its cls/F and Vd/F were both decreased,while its Cmax was elevated. In addition, Cmax of deacetyldiltiazem,an active metabolite of diltiazem, was also elevated.It was suggested that the metabolism of propafenone in liver may be inhibited by diltiazem and meanwhile propafenone may have an effect on the absorption or elimination of diltiazem. From the above result, it is essential for clinicians to monitor drug concentration when diltiazem is coadministed with propafenone,and in some case, dosage of these drugs should be adjusted.
A balanced, randomized and crossover study was conducted in six rabbits. Each rabbit was given diltiazem/propafenone alone or in combination. Pharmacokinetic parameters of propafenone were significantly changed when coadministration with diltiazem. Its Ke and cls/F were both Cmax and AUC0-∞ were increased. On the other hand, some pharmacokinetic parameters of diltiazem were also changed after combination treatment. Its cls/F and Vd/F were both decreased,while its Cmax was elevated. In addition, Cmax of deacetyldiltiazem,an active metabolite of diltiazem, was also elevated.It was suggested that the metabolism of propafenone in liver may be inhibited by diltiazem and meanwhile propafenone may have an effect on the absorption or elimination of diltiazem. From the above result, it is essential for clinicians to monitor drug concentration when diltiazem is coadministed with propafenone,and in some case, dosage of these drugs should be adjusted.
1995, (6): 359-361.
Abstract:
The paper reported the assay fo sodium acetate content in composite sodium acetate injection solution with neutralization method instead of ionexchange method. The method was applied according to sodium acetate in alcohol, glycerine composite solution titrated by hydrochloric acid solution, with had distinctly precipitate end-point, precise and reliable result and good reproducibility and recovery rate, with average recovery rate 99.99%,variation coefficient 0.16%.
The paper reported the assay fo sodium acetate content in composite sodium acetate injection solution with neutralization method instead of ionexchange method. The method was applied according to sodium acetate in alcohol, glycerine composite solution titrated by hydrochloric acid solution, with had distinctly precipitate end-point, precise and reliable result and good reproducibility and recovery rate, with average recovery rate 99.99%,variation coefficient 0.16%.
1995, (6): 361-363.
Abstract:
A colorimetric method for the determination of meprobamate tablete, was developed. The result of meprobamate agreed with those obtained by the ChP(1990) method. The recoveries of piperine was 99.85%(n=5).The method is specific,sensitive,simple,and rapid.
A colorimetric method for the determination of meprobamate tablete, was developed. The result of meprobamate agreed with those obtained by the ChP(1990) method. The recoveries of piperine was 99.85%(n=5).The method is specific,sensitive,simple,and rapid.
1995, (6): 363-365.
Abstract:
A first derivative UV-spectrophotometric method was successfully used without seperation for the determination of berberine in shaoshang Ⅱ hao tincture. The wavelength of determination was 361.3nm, the average recovery was 99.97%, RSD was 0.47% (n=5).The method is simple, rapid and accurate.
A first derivative UV-spectrophotometric method was successfully used without seperation for the determination of berberine in shaoshang Ⅱ hao tincture. The wavelength of determination was 361.3nm, the average recovery was 99.97%, RSD was 0.47% (n=5).The method is simple, rapid and accurate.
1995, (6): 371-374.
Abstract:
Antibiotic medicines are the most widely used medicines at present in hospitals. In order to direct the rational clinical use, make them efficient and reduce their harmful reaction as well, we make statistical analysis of the consumption of antibiotic medicines and the drug sensitive tist on clinical separated bacteria. The statistical result shows there is a certain ratio between the consumption of antibiotic medicines and the increase of drug resistant strain. So we should be aware of the consumption of the antibiotic medicines and the drug tolerance changes of the clinical bacteria as well. In this way we can direct the rational clinical use of antibiotic medicines correctly.
Antibiotic medicines are the most widely used medicines at present in hospitals. In order to direct the rational clinical use, make them efficient and reduce their harmful reaction as well, we make statistical analysis of the consumption of antibiotic medicines and the drug sensitive tist on clinical separated bacteria. The statistical result shows there is a certain ratio between the consumption of antibiotic medicines and the increase of drug resistant strain. So we should be aware of the consumption of the antibiotic medicines and the drug tolerance changes of the clinical bacteria as well. In this way we can direct the rational clinical use of antibiotic medicines correctly.
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