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2003 Vol. 21, No. 4

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2003, (4): 195-198.
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2003, (4): 198-201.
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2003, (4): 201-203.
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Preparation of cefoperazone ointment
XU Fang, ZHANG Guo-qing, XIN Yan-hong, YU Hai-chun, QU Yan, DUAN Yan-bing
2003, (4): 203-205.
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OBJECTIVE To prepare and establish quality standards of cefoperazone ointment. METHODS UV-spectrophotometry was used to determine the content of cefoperazone ointment. RESULTS The absorbance at 298nm showed a linear relationship in range of 0.8~4.8ug·mL-1, with mean recovery of 99.3%, RSD of 0.32%. CONCLUSIONS The method is accurate, simple, rapid and can be used to determine the content of cefoperazone ointment.
Advances in studies eucalyptus oil as a transdermal enhancer
MAO Qing-xiang, CHANG Wen-jun, CAI Quan-cai
2003, (4): 205-209.
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OBJECTIVE Introduce the development of the eucalyptus oil as a transdermal absorption enhancer. METHODS The transdermal absorption enhancing mechanism of eucalyptus oil and its application and influence factor were reviewed. RESULTS and CONCLUSION The eucalyptus oil is a good transdermal absorption enhancer and has a great future.
2003, (4): 209-210,216.
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2003, (4): 211-213.
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2003, (4): 213-213.
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Application of convolution curve method for simultaneous determination of four components in the compound children's phenobarbital tablet
GAO Jin-bo, DING Li-xin, HOU Wei, ZHANG Yu-nan, LU Ning
2003, (4): 214-216.
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OBJECTIVE Without any separation, simultaneous determination of four main components in the compound children's phenobarbital tablet. METHODS Based on convolution spectrometry with the excellent cacu-lation method-PLS method used convolution spectrometry of computer information process technology. RESULTS Components of compound children's phenobarbital tablet are aspirin, phenacetin, caffine and phenobarbital. Their average recoveries and RSD were 99.75,0.92%;100.47,0.56%;99.82,1.12%;100.08,0.86%. CONCLUSION The method is used for qualitative control of compound children's phenobarbital tablet.
2003, (4): 217-218.
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Determination of baicalin in Xiaoyan granules by RP-HPLC
QIN Hong-lin
2003, (4): 218-219.
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OBJECTIVE To determine the content of baicalin in Xiaoyan granules. METHODS Re verse-phase high performance liquid chromatography was established. A C18 column(250mmX 4. 6mm,5um)with mobile phase of MeOH:0. 2%phosphat(60:40)was used. The detection wavelength was 280nm. RESULTS:The mean recoveries were 100.64%(RSD-1.69%). CONCLUSION The method was rapid, sensitive and accurate.
Linear determination of puerarin and isoflavones in Radix Puerariae in Plasma
GUO Jian-ping, LI Guo-dong, ZHAO Tong-ying, FAN Wei
2003, (4): 219-221.
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OBJECTIVE To study the pharmacokinetics behavior of puerarin, isoflavones and its Products in human body, make the determination of puerarin and isoflavones in Radix Puerariae. METHODS Carry out the determination by HPLC. The chromatographic condition: the flow rate was 1mL·min-1. The temperature of the column was 20C:the detection wavelength was at 250nm. The mobile phase was consisted of methanol-water(25:75). RESULTS R = 6.56 RSD <5.02%. The average recoveries:(100.9 + 0.5)%, Linear range is 0.0295~0.708μg·mL-1 for puerarin and isoflavones in human plasma. CONCLUSIONS Pharmacokinetics of Puerarin and isoflavones in human plasma could be determined by HPLC, supplying the method for examining isoflavones in Radix Puerariae in human body.
Comparative investigation in the quality of three different size of powder in Lamiophlomis Rotata
WANG Xu-ming, ZHAO Xin, WANG Jing
2003, (4): 221-224.
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OBJECTIVE To study dissolution speciality of active substance of ultramicro-powder in Lamio-phlomis Rotata. METHODS Ultramicro-pulverization was applied to Lamiophlomis Rotata, to investigate dissolution speciality of active substance by TLC, gravimetric method and spectrophotometry. RESULTS:To be compared with coarse powder and fine powder, the active substance of ultramicro-powder can be extracted more efficiently. CONCLUSION Ultramicro-pulverization was applied to Lamiophlomis Rotata, the active substance could be extracted faster, accordingly the extraction of Chinese herbal medicinel can be predigest.
Study progress and clinical application on antifungal drugs
CAO Qin, FAN Wei, WANG Kai-wei
2003, (4): 225-228.
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OBJECTIVE To introduce the study progress and clinical application on antifungal drugs. METHODS By analyzing the literature about the antifungal drugs at home and abroad, study progress and clinical application on antifungal drugs were reviewed by classification. RESULTS & CONCLUTION: The study on the antifungal drugs is mainly concentrated on the structure reform and the discoveries of new antifungal drugs. In clinical, the antifungal drugs are being used according to its different characteristic.
2003, (4): 228-228.
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2003, (4): 229-230.
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2003, (4): 230-232.
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2003, (4): 233-233.
Abstract(1582) PDF (492KB)(432)
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2003, (4): 234-235.
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2003, (4): 235-236.
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2003, (4): 237-239.
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2003, (4): 239-240.
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2003, (4): 241-243.
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2003, (4): 244-244.
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2003, (4): 244-244.
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2003, (4): 245-245.
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2003, (4): 246-246.
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2003, (4): 247-248.
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2003, (4): 248-248.
Abstract(1592) PDF (608KB)(407)
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2003, (4): 249-255.
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