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应中央军委要求,2022年9月起,《药学实践杂志》将更名为《药学实践与服务》,双月刊,正文96页;2023年1月起,拟出版月刊,正文64页,数据库收录情况与原《药学实践杂志》相同。欢迎作者踊跃投稿!

细胞外激活纳米载药系统研究进展

王晓宇 高静 张玮 朱全刚 武鑫 高申

王晓宇, 高静, 张玮, 朱全刚, 武鑫, 高申. 细胞外激活纳米载药系统研究进展[J]. 药学实践与服务, 2012, 30(1): 4-7,57. doi: 10.3969/j.issn.1006-0111.2012.01.002
引用本文: 王晓宇, 高静, 张玮, 朱全刚, 武鑫, 高申. 细胞外激活纳米载药系统研究进展[J]. 药学实践与服务, 2012, 30(1): 4-7,57. doi: 10.3969/j.issn.1006-0111.2012.01.002
WANG Xiao-yu, GAO Jing, ZHANG Wei, ZHU Quan-gang, WU Xin, GAO Shen. Progress on extracellularly activated nanocarriers[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(1): 4-7,57. doi: 10.3969/j.issn.1006-0111.2012.01.002
Citation: WANG Xiao-yu, GAO Jing, ZHANG Wei, ZHU Quan-gang, WU Xin, GAO Shen. Progress on extracellularly activated nanocarriers[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(1): 4-7,57. doi: 10.3969/j.issn.1006-0111.2012.01.002

细胞外激活纳米载药系统研究进展

doi: 10.3969/j.issn.1006-0111.2012.01.002
基金项目: 国家自然科学基金(81172514,30873178).

Progress on extracellularly activated nanocarriers

  • 摘要: 隐蔽性和靶向性对于纳米载体能否高效、选择性的递送药物非常重要,然而,传统方法难以让纳米载体同时具备这两种性质。新型靶向技术的迅速发展有望克服这一难点。本文在回顾传统靶向技术,阐述其取得的成果和面临的瓶颈的同时,着重讨论了利用环境刺激来激活的新型纳米载体的研究进展。
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    [17] Ko, J., et al.Tumoral acidic extracellular pH targeting of pH-responsive MPEG-poly(beta-amino ester) block copolymer micelles for cancer therapy[J]. J Control Release, 2007,123(2): 109.
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出版历程
  • 收稿日期:  2011-05-07
  • 修回日期:  2011-06-02

细胞外激活纳米载药系统研究进展

doi: 10.3969/j.issn.1006-0111.2012.01.002
    基金项目:  国家自然科学基金(81172514,30873178).

摘要: 隐蔽性和靶向性对于纳米载体能否高效、选择性的递送药物非常重要,然而,传统方法难以让纳米载体同时具备这两种性质。新型靶向技术的迅速发展有望克服这一难点。本文在回顾传统靶向技术,阐述其取得的成果和面临的瓶颈的同时,着重讨论了利用环境刺激来激活的新型纳米载体的研究进展。

English Abstract

王晓宇, 高静, 张玮, 朱全刚, 武鑫, 高申. 细胞外激活纳米载药系统研究进展[J]. 药学实践与服务, 2012, 30(1): 4-7,57. doi: 10.3969/j.issn.1006-0111.2012.01.002
引用本文: 王晓宇, 高静, 张玮, 朱全刚, 武鑫, 高申. 细胞外激活纳米载药系统研究进展[J]. 药学实践与服务, 2012, 30(1): 4-7,57. doi: 10.3969/j.issn.1006-0111.2012.01.002
WANG Xiao-yu, GAO Jing, ZHANG Wei, ZHU Quan-gang, WU Xin, GAO Shen. Progress on extracellularly activated nanocarriers[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(1): 4-7,57. doi: 10.3969/j.issn.1006-0111.2012.01.002
Citation: WANG Xiao-yu, GAO Jing, ZHANG Wei, ZHU Quan-gang, WU Xin, GAO Shen. Progress on extracellularly activated nanocarriers[J]. Journal of Pharmaceutical Practice and Service, 2012, 30(1): 4-7,57. doi: 10.3969/j.issn.1006-0111.2012.01.002
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