紫外分光光度法测定枸橼酸乙胺嗪片的含量
Determination of diethylcarbamazine tablet by ultraviolet spectrophotometry
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摘要: 本文依据枸橼酸乙胺嗪在211nm波长处有最大吸收,拟定了紫外分光度法测定其片剂的含量。对定量条件进行了考察,测定液浓度在15.31μg/ml范围内,浓度(C)与吸收度(A)呈良好的线性关系,r=0.9999,平均回收率为100.42%,RSD=0.61%(n=8).该法简便,样液稳定,节省试剂,赋形剂对测定无干扰。测定结果与药典法对照,无显着性差异(P>0.05)。Abstract: The Content of the Diethylcarbamazine tablet was determined by ultraviolet spectrophotometry. The detecting wavelength was 211 nm, there was a good linear correlation in the range of 15~31μg/ml(r=0.9999).The average recovery was 100.42% with RSD of 0.61%(n=8). The results showed that the method was simple, stable and saving agents, there was no statistical difference between the results measured by the nonaqueous titration in Chinese Pharmacopea(1990)and by UV(P>0.05).
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Key words:
- Diethylcarbamazine tablet /
- content assay /
- ultroviolet spectrophotometry
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