复方鱼腥草配方合煎对黄芩苷和绿原酸成分溶出量的影响
Effect on dissolution of baicalin and chlorogenic acid in Compound Herba Houttuyniae in different combinations
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摘要: 目的: 比较复方鱼腥草全方合煎与药材单煎对黄芩苷和绿原酸成分溶出量的影响。 方法: 采用高效液相色谱法,测定黄芩和金银花药材单煎提取物、全方合煎提取物中黄芩苷与绿原酸的含量。 结果: 全方合煎中的黄芩苷溶出量比黄芩单煎增加100%,相反,全方合煎中的绿原酸溶出量比金银花单煎降低25.4%。 结论: 复方配伍后煎煮对成分的溶出量有明显影响。Abstract: Objective: To investigate the dissolution of baicalin and chlorogenic acid in decoctions of Composition Herba Houttuyniae and simple recipe. Methods: The contents of baicalin and chlorogenic acid were determined in decoctions of Composition Herba Houttuyniae and simple recipe by HPLC. Results: The decoctions of composition Herba Houttuyniae were compared with simple recipe: the content of baicalin in the former decreased 100%,and the chlorogenic acid decreased 25.4%. Conclusion: Different combinations of complex prescription of Chinese herbal medicine in the form have great influence on the dissolution of chemical component content.
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Key words:
- composition herba houttuyniae /
- baicalin /
- chlorogenic acid /
- HPLC /
- compatibility
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