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应中央军委要求,2022年9月起,《药学实践杂志》将更名为《药学实践与服务》,双月刊,正文96页;2023年1月起,拟出版月刊,正文64页,数据库收录情况与原《药学实践杂志》相同。欢迎作者踊跃投稿!

药师在药物基因组学临床实践中的角色

傅翔 李向荣

傅翔, 李向荣. 药师在药物基因组学临床实践中的角色[J]. 药学实践与服务, 2017, 35(6): 569-572. doi: 10.3969/j.issn.1006-0111.2017.06.022
引用本文: 傅翔, 李向荣. 药师在药物基因组学临床实践中的角色[J]. 药学实践与服务, 2017, 35(6): 569-572. doi: 10.3969/j.issn.1006-0111.2017.06.022
FU Xiang, LI Xiangrong. The role of pharmacist in clinical pharmacogenomics[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(6): 569-572. doi: 10.3969/j.issn.1006-0111.2017.06.022
Citation: FU Xiang, LI Xiangrong. The role of pharmacist in clinical pharmacogenomics[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(6): 569-572. doi: 10.3969/j.issn.1006-0111.2017.06.022

药师在药物基因组学临床实践中的角色

doi: 10.3969/j.issn.1006-0111.2017.06.022

The role of pharmacist in clinical pharmacogenomics

  • 摘要: 药物基因组学的临床实践推动着精准医学的发展。笔者从一名药师的角度,分析药师在药物基因组学临床应用中的主导作用和具体职责,并从国外现阶段的应用实例中探讨药师所面临的挑战和相应对策,为药师今后开展相关服务和实践提供参考。
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    [7] O'Connor SK, Ferreri SP, Michaels NM,et al.Exploratory planning and implementation of a pilot pharmacogenetic program in a community pharmacy[J]. Pharmacogenomics, 2012,13(8):955-962.
    [8] ASHP statement on the pharmacist's role in clinical pharmacogenomics[J]. Am J Health Syst Pharm, 2015,72(7):579-581.
    [9] Genetics/genomics competency map for pharmacists[EB/OL].[2015-08-20].http://g-2-c-2.org/competency/pharmacist.
    [10] Ferro WG, Kuo GM, Jenkins JF, et al. Pharmacist education in the era of genomic medicine[J]. J Am Pharm Assoc(2003),2012,52(5):e113-e121.
    [11] Hicks JK, Crews KR, Hoffman JM, et al. A cliniciandriven automated system for integration of pharmacogenetic interpretations into an electronic medical record[J]. Clin Pharmacol Ther,2012,92(5):563-566.
    [12] Budnitz DS, Lovegrove MC, Shehab N, et al. Emergency hospitalizations for adverse drug events in older Americans[J]. N Engl J Med,2011,365(21):2002-2012.
    [13] American society of health-system pharmacists. ASHP policy positions 1982-2013[EB/OL].http://www.ashp.org/DocLibrary/BestPractices/policypositionsonly2013.aspx.
    [14] Crews KR, Cross SJ, McCormick JN, et al. Development and implementation of a pharmacist-managed clinical pharmacogenetics service[J]. Am J Health Syst Pharm, 2011,68(2):143-150.
    [15] Charland SL, Agatep BC, Herrera V, et al. Providing patients with pharmacogenetic test results affects adherence to statin therapy:results of the additional KIF6 risk offers better adherence to statins (AKROBATS) trial[J]. Pharmacogenomics J, 2014,14(3):272-280.
    [16] Kisor DF, Bright DR, Conaway M, et al. Pharmacogenetics in the community pharmacy:thienopyridine selection post-coronary artery stent placement[J]. J Pharm Pract, 2014,27(4):416-419.
    [17] Pharmacists' role in pharmacogenomics increasing in an age of precision medicine[EB/OL].[2016-08-03].http://www.pharmacytoday.org/article/S1042-0991(16)30528-X/fulltext.
    [18] Shin J, Kayser SR, Langaee TY. Pharmacogenetics:from discovery to patient care[J]. Am J Health Syst Pharm, 2009,66(7):625-637.
    [19] Relling MV, Klein TE. CPIC:clinical pharmacogenetics implementation consortium of the pharmacogenomics research network[J]. Clin Pharmacol Ther,2011,89(3):464-467.
    [20] Pharmacogenomics knowledge base. Drug labels[EB/OL].http://www.pharmgkb.org/view/drug-labels.do
    [21] Table of pharmacogenomic biomarkers in druglabeling[EB/OL].http://www.fda.gov/drugs/scienceresearch/researchareas/pharmacogenetics/ucm083378.htm
    [22] 徐婵娟,徐玉萍,王春松,等.临床药师参与1例华法林个体化抗凝中基因型检测的临床实践[J].中国医院用药评价与分析,2015,15(9):1256-1258.
    [23] 刘洪涛,连玉菲,庞国勋,等.临床药师参与1例老年心血管病患者的个体化抗血小板治疗实践[J].药学与临床研究,2016,24(2):170-171.
    [24] 魏安华,顾智淳,李娟,等.3例氯吡格雷抵抗患者的药学监护[J].医药导报,2015, 34(12):1668-1670.
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  • 收稿日期:  2017-05-10
  • 修回日期:  2017-06-19

药师在药物基因组学临床实践中的角色

doi: 10.3969/j.issn.1006-0111.2017.06.022

摘要: 药物基因组学的临床实践推动着精准医学的发展。笔者从一名药师的角度,分析药师在药物基因组学临床应用中的主导作用和具体职责,并从国外现阶段的应用实例中探讨药师所面临的挑战和相应对策,为药师今后开展相关服务和实践提供参考。

English Abstract

傅翔, 李向荣. 药师在药物基因组学临床实践中的角色[J]. 药学实践与服务, 2017, 35(6): 569-572. doi: 10.3969/j.issn.1006-0111.2017.06.022
引用本文: 傅翔, 李向荣. 药师在药物基因组学临床实践中的角色[J]. 药学实践与服务, 2017, 35(6): 569-572. doi: 10.3969/j.issn.1006-0111.2017.06.022
FU Xiang, LI Xiangrong. The role of pharmacist in clinical pharmacogenomics[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(6): 569-572. doi: 10.3969/j.issn.1006-0111.2017.06.022
Citation: FU Xiang, LI Xiangrong. The role of pharmacist in clinical pharmacogenomics[J]. Journal of Pharmaceutical Practice and Service, 2017, 35(6): 569-572. doi: 10.3969/j.issn.1006-0111.2017.06.022
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