2024 Vol. 42, No. 5
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2024, 42(5): 181-184, 197.
doi: 10.12206/j.issn.2097-2024.202312023
Abstract:
With the increasing prevalence of diabetes, the prevention and treatment of diabetes nephropathy have become a worldwide problem. The molecular mechanism of the occurrence and development of diabetes nephropathy is still unclear, but many studies in ...
With the increasing prevalence of diabetes, the prevention and treatment of diabetes nephropathy have become a worldwide problem. The molecular mechanism of the occurrence and development of diabetes nephropathy is still unclear, but many studies in ...
2024, 42(5): 185-189.
doi: 10.12206/j.issn.2097-2024.202307052
Abstract:
Maslinic acid is a pentacyclic triterpenoid that is widely found in natural plants such as olives and hawthorns. Maslinic acid has anti-tumor, anti-inflammation, anti-oxidation, antibacterial, cardiovascular protection, neuroprotection, and other pha...
Maslinic acid is a pentacyclic triterpenoid that is widely found in natural plants such as olives and hawthorns. Maslinic acid has anti-tumor, anti-inflammation, anti-oxidation, antibacterial, cardiovascular protection, neuroprotection, and other pha...
2024, 42(5): 190-197.
doi: 10.12206/j.issn.2097-2024.202310004
Abstract:
Objective To evaluate the pharmacodynamics of astragaloside Ⅳ derivatives for chronic heart failure, screen the candidate compounds and preliminarily explore the mechanism of the candidate compound HHQ16 against heart failure. Methods Chronic...
2024, 42(5): 198-202, 222.
doi: 10.12206/j.issn.2097-2024.202311014
Abstract:
Objective To generate mice with whole-body overexpression of human METRNL gene. Methods Based on Cre-loxP system, Dppa3-Cre mice were mated with Rosa26-LSL-METRNL knock-in mice（R26-LSL-METRNL+/-）to generate R26-L-METRNL+/- mice. The genotypes ...
2024, 42(5): 203-210, 216.
doi: 10.12206/j.issn.2097-2024.202211012
Abstract:
Objective To screen the pharmacodynamic material basic components of Artemisiae Annuae Herba and study its antioxidant activity in vitro by investigating the spectrum-effect relationship between the HPLC fingerprints of 11 batches of Artemisiae Ann...
2024, 42(5): 211-216.
doi: 10.12206/j.issn.2097-2024.202306031
Abstract:
Objective To establish a mice model of atopic dermatitis with acute itching and investigate the antipruritic effect and its mechanism of Xiaofeng Zhiyang granules（XFZYG）. Methods A mice model of atopic dermatitis was prepared by induction meth...
2024, 42(5): 217-222.
doi: 10.12206/j.issn.2097-2024.202311029
Abstract:
Objective To explore the correlation between the immune related adverse （irAEs） reactions in patients treated with pembrolizumab and traditional Chinese Medicine （TCM） constitution. Methods A total of 110 patients diagnosed with non-small cell...
2024, 42(5): 223-226.
doi: 10.12206/j.issn.2097-2024.202310042
Abstract:
Objective To investigate the risk factors of infection of Pseudomonas aeruginosa combined with Elizabethkingia anophelis in patients with cerebral hemorrhage and the antimicrobial treatment plan. Methods Clinical pharmacists participated in th...
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