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2024 Vol. 42, No. 6

Cover Catalogue
Display Method:
Application of machine learning in individualized medication of tacrolimus in patients with nephrotic syndrome
DING Qianxue, SHANG Shenglan, YU Mengchen, YU Airong
2024, 42(6): 227-230, 243. doi: 10.12206/j.issn.2097-2024.202310007
Abstract(4125) HTML (1745) PDF (1278KB)(37)
Abstract:
Tacrolimus is a commonly used medication for the treatment of nephrotic syndrome. Due to its narrow therapeutic window and significant pharmacokinetic differences among individuals, therapeutic drug monitoring is required during its clinical use. In ...
Research progress on targeted therapy and immunotherapy for esophageal cancer
MA Zifen, XU Weiheng, JIN Yuxiang, XUE Lei
2024, 42(6): 231-237. doi: 10.12206/j.issn.2097-2024.202306008
Abstract(9457) HTML (3619) PDF (877KB)(102)
Abstract:
Esophageal cancer is a malignant tumor with high incidence and mortality rate in the world and its pathogenic factors are complex and diverse. There are no obvious symptoms in the early stage, and most patients are in the middle to late stage at the ...
Review of drug utilization research based on real-world data
ZHANG Yuanlin, SONG Kai, SUN Rui, SHU Fei, SHU Lixin, YANG Zhangwei
2024, 42(6): 238-243. doi: 10.12206/j.issn.2097-2024.202312010
Abstract(7572) HTML (2818) PDF (980KB)(94)
Abstract:
In recent years, the rapid development of medical information technology has made it critical to analyze large-scale diagnosis and therapeutic data and extract rules based on real medical environment. This has become an essential approach for marketi...
Synergistic effect of positive electret combined with 5-fluorouracil on growth inhibition of scar fibroblasts
YANG Yuanyuan, AN Xiaoqiang, XU Jiajie, JIANG Jian, LIANG Yuanyuan
2024, 42(6): 244-247. doi: 10.12206/j.issn.2097-2024.202310027
Abstract(4485) HTML (1087) PDF (1146KB)(9)
Abstract:
Objective   To investigate the effects and possible mechanism of electret and 5-fluorouracil(5-FU)on the growth of scar fibroblasts.   Methods   The effect of +5000 V electret combined with different concentrations of 5-FU on the proliferation of ...
Determination of four different components in Danggui Liuhuang decoction by HPLC-MS/MS
LI Dan, DAI Xianchun, WANG Fangzhen, CHEN Yihan, YANG Ping, LIU Jiyong
2024, 42(6): 248-252, 266. doi: 10.12206/j.issn.2097-2024.202305007
Abstract(5462) HTML (2506) PDF (1353KB)(40)
Abstract:
Objective  To establish the method of simultaneous determination of four main components of Danggui Liuhuang Decoction, including phellodendrine, palmatine, calycosin, and ferulic acid and provide reference for the quality control of Danggui Liuhuan...
Induction of apoptosis in triple-negative breast cancer cells by petroleum ether extract of Sageretia thea
FENG Zhihui, DENG Yiqing, YE Bing, AN Pei, ZHANG Hong, ZHANG Haijun
2024, 42(6): 253-259. doi: 10.12206/j.issn.2097-2024.202311055
Abstract(3521) HTML (843) PDF (2285KB)(9)
Abstract:
Objective  To investigate the effect of the petroleum ether extract of Sageretia thea on the proliferation and apoptosis of breast cancer cells.   Methods  After breast cancer cells were incubated with the petroleum ether extract for different tim...
Distribution characteristics and drug resistance rate of pathogenic bacteria in patients with pulmonary tuberculosis combined with Candida infection on the Tibetan plateau
SHI Shenghui, SHI Fei, LEI Qiong, WANG Yafeng, WU Xuehua
2024, 42(6): 260-262, 272. doi: 10.12206/j.issn.2097-2024.202304014
Abstract(4250) HTML (1037) PDF (1267KB)(15)
Abstract:
Objective  To investigate the pathogenic distribution characteristics and drug resistance of opportunistic Candida in patients with pulmonary tuberculosis on the Qinghai-Tibet Plateau.   Methods  3 012 hospitalized cases of pulmonary tuberculosis ...
Participation of clinical pharmacists in QTc interval prolongation induced by gilteritinib
CUI Xiaolin, FU Xiaofei, DU Yanhong, LIU Juan, ZHU Qian, LIU Ziqi
2024, 42(6): 263-266. doi: 10.12206/j.issn.2097-2024.202309050
Abstract(5664) HTML (1461) PDF (1092KB)(22)
Abstract:
Objective  To explore the role of clinical pharmacists involved in the case of a patient with acute myeloid leukemia whose QTc interval prolongation was induced by gilteritinib, and to provide reference for drug treatment and monitoring of those pat...
Analysis of clinical characteristics and anti-infection treatment of 89 cases with pyogenic liver abscess
ZHANG Jingjing, SUO Li’na, ZHENG Zhaohong
2024, 42(6): 267-272. doi: 10.12206/j.issn.2097-2024.202302039
Abstract(4474) HTML (3143) PDF (966KB)(14)
Abstract:
Objective  To analyze the clinical characteristics of pyogenic liver abscess(PLA)and explore the rationality and the duration of antibacterial treatment.   Methods  The clinical data of patients diagnosed as pyogenic liver abscess in our hospital ...