盐酸丁咯地尔与5种输液配伍的稳定性研究
The study on the stability of buflomedil hydrochloride in five injection solution
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摘要: 目的 研究盐酸丁咯地尔在 5%葡萄糖注射液、10%葡萄糖注射液、0.9%氯化钠注射液、注射用水 5%碳酸氢钠注射液 5种输液中的稳定性。方法 用紫外分光光度法测定盐酸丁咯地尔的含量,并观察输液的外观、pH值及盐酸丁咯地尔紫外光谱的变化。结论 盐酸丁咯地尔的 5种输液混和液在 25℃、37℃下放置 9h内含量均在 98.5%以上。结论 可以配伍应用。Abstract: OBJECTIVE To study the five stability of buflomedil hydrochloride in five injection solutions METHODS The content of buflomedil hydrochloride was determined by UV spectrophotometery The appearance Ph and change of buflomedil hydrochloride of UV spectrum in 9 hours RESULTS Buflomedil hydrochloride in five injection solution at 25℃、37℃ in 9 hours was stable The quantity of buflomedil hydrochloride was over 98.5%.CONCLUSION The solutions prepared were compatible and clinical applicable.
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Key words:
- buflomedil hydrochloride /
- stability /
- compatibility
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