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分子印迹技术在药物分离中的研究进展

孔丹凤 赵雯 卢婷利 惠倩倩 王韵晴 陈涛

孔丹凤, 赵雯, 卢婷利, 惠倩倩, 王韵晴, 陈涛. 分子印迹技术在药物分离中的研究进展[J]. 药学实践与服务, 2011, 29(3): 161-164.
引用本文: 孔丹凤, 赵雯, 卢婷利, 惠倩倩, 王韵晴, 陈涛. 分子印迹技术在药物分离中的研究进展[J]. 药学实践与服务, 2011, 29(3): 161-164.
KONG Dan-feng, ZHAO Wen, LU Ting-li, HUI Qian-qian, WANG Yun-qing, CHEN Tao. Progress of molecular imprinting technique in drug separation[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(3): 161-164.
Citation: KONG Dan-feng, ZHAO Wen, LU Ting-li, HUI Qian-qian, WANG Yun-qing, CHEN Tao. Progress of molecular imprinting technique in drug separation[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(3): 161-164.

分子印迹技术在药物分离中的研究进展

Progress of molecular imprinting technique in drug separation

  • 摘要: 分子印迹聚合物(molecularly imprinted polymer,MIPS)由于对分子具有特异性识别功能在近年来受到了各界科学家的广泛关注。其中MIPS在药物分离方面研究占了相当大的比例,从混合物中提取目标药物,分离结构类似物,以及手性结构药物的分离,MIPS的功能在不断强大,它在药物分离领域的地位也在不断提升。本文综述了MIPS在药物分离中的研究, MIPS功能单体的选择并预言了未来的发展方向。
  • [1] Wulff G, sarhan A, zabrock I. Enzyme analogue built polymers and their use for the resolution of racemates[J].Tetrahedron Lett, 1973, 44: 4329.
    [2] 蔡万锡.天然维生素E提取工艺的比较[J].生化与医药-化工之友,2007,1:48.
    [3] 曾哲灵,万冬满,陈 力,等.天然维生素E提取工艺研究[J].中国畜产与食品,1997,4(1):27.
    [4] Faizal CKM, Hoshina Y, Kobayashi T.Scaffold membranes for selective adsorption of α-tocopherol by phase inversion covalently imprinting technique[J].Journal of Membrane Science,2008,322:503.
    [5] Faizal CKM, Kikuchic Y, Kobayashi T. Molecular imprinting targeted for α-tocopherol by calix resorcarenes derivative in membrane scaffold prepared by phase inversion[J].Journal of Membrane Science,2009,334:110.
    [6] Piacham T, Nantasenamat C, Suksrichavalit T,et al. Synthesis and theoretical study of molecularly imprinted nanospheres for recognition of tocopherols[J].Molecules,2009,14: 2985.
    [7] Wang P, Hu WM, Su WK. Molecularly imprinted poly(methacrylamide-co-methacrylic acid) composite membranes for recognition of curcumin[J].Analytica Chimica,2008,615:54.
    [8] Zhang YQ, Gao XQ, Wang YL,et al. Study on the build of channels in accurate separation membrane and its selective mechanism[J].Journal of Membrane Science,2009,339:100.
    [9] Zhai CX, Lu Q, Chen XM,et al. Molecularly imprinted layer-coated silica nanoparticles toward highly selective separation of active diosgenin from dioscorea nipponica makino[J]. Journal of Chromatography A,2009,1216:2254.
    [10] 曹永兵,雷 孝,王 锦,等. 分子印迹技术在药学中的应用进展[J].广州化学,2008,33(4):56.
    [11] Ansell RJ. Molecularly imprinted polymers for the enantioseparation of chiral drugs[J].Advanced Drug Delivery Reviews,2005,57:1809.
    [12] Wang JY, Xu ZL, Wu P,et al. Binding constant and transport property of S-naproxen molecularly imprinted composite membrane[J].Journal of Membrane Science,2009,331:84.
    [13] Xu ZY,Wan JF, Liang S,et al. Separation of ursodeoxycholic acid from its isomeric mixture using core-shell molecular imprinting polymer[J].Biochemical Engineering Journal,2008,41:280.
    [14] Wang XJ, Xu ZL, Feng JL,et al. Molecularly imprinted membranes for the recognition of lovastatin acid in aqueous medium by a template analogue imprinting strategy[J].Journal of Membrane Science,2008,313:97.
    [15] Huang JY, Wei ZX, Chen JC. Molecular imprinted polypyrrole nanowires for chiral amino acid recognition[J]. Sensors and Actuators B: Chemical,2008,134:573.
    [16] Panahi R, Vasheghani-Farahani E, Shojaosadati SA. Separation of l-lysine from dilute aqueous solution using molecular imprinting technique[J].Biochemical Engineering Journal,2007,35:352.
    [17] Papaioannou E, Koutsas C, Liakopoulou-Kyriakides M. Molecularly imprinted polymers for RGD selective recognition and separation[J].Amino Acids,2009, 36:563.
    [18] Itou Y, Nakano M, Yoshikawa M. Optical resolution of racemic amino acid derivatives with molecularly imprinted membranes from tetrapetide consisting of glycinyl residues[J].Journal of Membrane Science,2008,325:371.
    [19] 石屹峰,边 蕾. 以人血清白蛋白为载体的长效蛋白质药物的研究进展[J].中国医药生物技术,2008,3(6):454.
    [20] Li L, HE XW,Chen LX, et al. Preparation of novel bovine hemoglobin surfaceimprinted polystyrene nanoparticles with magnetic susceptibility[J].Science in China Series B: Chemistry,2009,52(9):1402.
    [21] Lu Y, Yan CL, Gao SY. Preparation and recognition of surface molecularly imprinted core-shell microbeads for protein in aqueous solutions[J].Applied Surface Science,2009,255:6061.
    [22] Zhang W, Qin L, He XW, et al.Novel surface modified molecularly imprinted polymer using acryl-β-cyclodextrin and acrylamide as monomers for selective recognition of lysozyme in aqueous solution[J].Journal of Chromatography A,2009,1216:4560.
    [23] Qin L, He XW, Zhang W,et al.Surface-modified polystyrene beads as photografting imprinted polymer matrix for chromatographic separation of protein[J].Journal of Chromatography A,2009,1216:807.
    [24] Bolisaya LD, Culverb JN, Kofinas P. Molecularly imprinted polymers for tobacco mosaic virus recognition[J].Biomaterials,2006,27:4165.
    [25] 迟大民,苏立强,邓茜珊,等.分子印迹功能单体选择方法研究进展[J].化工时刊,2009,12(23):55.
    [26] 林秋明,何建峰,刘 岚,等.不同功能单体合成的分子印迹聚合物识别性能的研究[J].化学研究与应用,2007,10(19):1084.
    [27] Kowalska A, Stobiecka A, Wysocki S.A computational investigation of the interactions between harmane and the functional monomers commonly used in molecular imprinting[J].Journal of Molecular Structure: THEOCHEM,2009,901:88.
    [28] Chen ZD, Wei JX, Wang WC,et al.Separation of tryptophan enantiomers with molecularly imprinted polypyrrole electrode column[J].Chinese Chemical Letters,2010,21:353.
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  • 收稿日期:  2010-04-14
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分子印迹技术在药物分离中的研究进展

摘要: 分子印迹聚合物(molecularly imprinted polymer,MIPS)由于对分子具有特异性识别功能在近年来受到了各界科学家的广泛关注。其中MIPS在药物分离方面研究占了相当大的比例,从混合物中提取目标药物,分离结构类似物,以及手性结构药物的分离,MIPS的功能在不断强大,它在药物分离领域的地位也在不断提升。本文综述了MIPS在药物分离中的研究, MIPS功能单体的选择并预言了未来的发展方向。

English Abstract

孔丹凤, 赵雯, 卢婷利, 惠倩倩, 王韵晴, 陈涛. 分子印迹技术在药物分离中的研究进展[J]. 药学实践与服务, 2011, 29(3): 161-164.
引用本文: 孔丹凤, 赵雯, 卢婷利, 惠倩倩, 王韵晴, 陈涛. 分子印迹技术在药物分离中的研究进展[J]. 药学实践与服务, 2011, 29(3): 161-164.
KONG Dan-feng, ZHAO Wen, LU Ting-li, HUI Qian-qian, WANG Yun-qing, CHEN Tao. Progress of molecular imprinting technique in drug separation[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(3): 161-164.
Citation: KONG Dan-feng, ZHAO Wen, LU Ting-li, HUI Qian-qian, WANG Yun-qing, CHEN Tao. Progress of molecular imprinting technique in drug separation[J]. Journal of Pharmaceutical Practice and Service, 2011, 29(3): 161-164.
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