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沙门菌是常见的导致食源性细菌疾病的肠杆菌科细菌,主要通过污染食物、饮水引起感染,临床表现为腹痛、腹泻,常见于胃肠炎、肠热病等[1-2],但也可能发生发病率和死亡率较高的侵袭性疾病,演变为菌血症或影响肺部、中枢神经系统、肾脏、皮下组织、骨骼和关节的局部感染。这类侵袭性疾病主要发生于儿童、老年人、免疫抑制以及营养不良等人群[3-4]。本文报道了一例没有基础疾病、沙门菌致髋关节假体感染并且反复出现皮肤瘙痒的高龄患者。
A case analysis of a patient with salmonella infection and allergy to antibiotics
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摘要:
目的 通过临床药师参与髋关节假体感染的治疗,探讨沙门菌感染因素及皮肤瘙痒原因,提高对沙门菌感染的重视度及抗菌药不良反应的药学监护。 方法 通过查阅文献分析沙门菌感染原因及治疗方式,并监护各项指标和患者的临床症状,分析该患者出现皮肤瘙痒的原因,为患者提供合理抗感染治疗方案。 结果 住院期间经过多次抗菌药物调整,患者炎症指标下降,症状体征好转。 结论 虽然沙门菌引起的假体关节感染非常少见,但在临床上也要重视,同时,临床药师在日常工作中均应提高对抗菌药的监护力度。 Abstract:Objective Through clinical pharmacists participating in the treatment of hip prosthesis infection, to explore the factors of Salmonella infection and skin itching, and to increase the importance of Salmonella infection and the pharmaceutical monitoring of adverse reactions of antibiotics. Methods The causes and treatment of Salmonella infection were analyzed by reviewing the literature, monitoring indicators and patient's clinical symptoms, and analyzing the cause of the patient's skin itching, to provide the patient with a reasonable anti-infective treatment plan. Results After several antibacterial drug adjustments during hospitalization, the patient's inflammatory indicators decreased, and the clinical symptoms improved. Conclusion Although the prosthetic joint infection caused by Salmonella is very rare, attention should be paid to the detection of Salmonella. At the same time, clinical pharmacists should increase the monitoring of antibiotics in their daily work. -
Key words:
- Salmonella /
- hip prosthesis infection /
- antibiotics /
- skin itching
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